{"id":"W4307362132","doi":"10.1111/liv.15465","title":"A phase 2, open‐label, randomized, multiple‐dose study evaluating Inarigivir in treatment‐naïve patients with chronic hepatitis B","year":2022,"lang":"en","type":"article","venue":"Liver International","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Society of Intestinal Research; University of Calgary; Toronto Liver Centre; North York General Hospital; Toronto General Hospital; University of Toronto","funders":"","keywords":"Placebo; Medicine; HBsAg; Internal medicine; Gastroenterology; Hepatitis B virus; Adverse effect; Hepatitis B; Randomized controlled trial; Lamivudine; Immunology; Virus; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002386003,0.001840331,0.003160991,0.000460237,0.0005453939,0.001098299,0.001141164,0.001820879,0.006274536],"category_scores_gemma":[0.001740478,0.001131633,0.00144932,0.0004004383,0.001410938,0.001392358,0.0004306106,0.003100279,0.001200336],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000788793,"about_ca_system_score_gemma":0.001225188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008370297,"about_ca_topic_score_gemma":0.00166606,"domain_scores_codex":[0.9991158,0.0005203886,0.00004374664,0.0001383757,0.00006813902,0.0001135822],"domain_scores_gemma":[0.9987774,0.0002759928,0.0002527262,0.000134415,0.000102797,0.0004566288],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9504613,0.02766466,0.001404793,0.0003716237,0.0006133756,0.00005518118,0.00008746094,0.0003239476,0.006299281,0.00007352962,0.0005513651,0.01209348],"study_design_scores_gemma":[0.8851178,0.1119366,0.00179592,0.00001127725,0.0001426303,0.00003223532,0.0000188331,0.0002359431,0.0002972524,0.00006445389,0.0003346435,0.00001230759],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907126,0.001710539,0.0007458656,0.0004485917,0.0003058809,0.003968821,0.0006631896,0.0001110561,0.001333516],"genre_scores_gemma":[0.9852336,0.001433504,0.002720449,0.001330184,0.0004069904,0.00486788,0.0009671088,0.00003271459,0.003007674],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006274536,"threshold_uncertainty_score":0.02099037,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06352415516912682,"score_gpt":0.3793821792646608,"score_spread":0.315858024095534,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}