{"id":"W4307393395","doi":"10.1016/j.fertnstert.2022.08.297","title":"NONSELECTION, PILOT STUDY TO ASSESS THE CLINICAL EFFICACY OF NONINVASIVE PREIMPLANTATION GENETIC TESTING FOR ANEUPLOIDY","year":2022,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Fertility Centre","funders":"","keywords":"Concordance; Aneuploidy; Medicine; Predictive value; Selection (genetic algorithm); Clinical trial; Genetic testing; Prospective cohort study; Biopsy; Gynecology; Obstetrics; Oncology; Internal medicine; Biology; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002304119,0.001278371,0.001737861,0.0004920805,0.0005913472,0.0005059952,0.000677273,0.001108025,0.002933776],"category_scores_gemma":[0.003063324,0.0003174431,0.0006076492,0.0003433108,0.001823563,0.0008240243,0.0003514686,0.001963246,0.0005630407],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004019971,"about_ca_system_score_gemma":0.0008352467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006058415,"about_ca_topic_score_gemma":0.0009138903,"domain_scores_codex":[0.9988893,0.0005544552,0.00006290033,0.0002279267,0.0001404289,0.0001250697],"domain_scores_gemma":[0.9963453,0.001896615,0.000328906,0.0004488445,0.0001725679,0.0008077815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.6236662,0.1871552,0.01383952,0.0003087258,0.0004402229,0.001436617,0.0003553636,0.0007243929,0.1041647,0.0002568787,0.001403934,0.06624819],"study_design_scores_gemma":[0.03430586,0.948603,0.01246596,0.000005580088,0.0001234625,0.0002820673,0.00004989555,0.0003698449,0.003210438,0.00006356354,0.0005064868,0.00001388866],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972531,0.0004180705,0.0004817119,0.0001182367,0.00008161089,0.0006237469,0.0001577637,0.00003772668,0.000828169],"genre_scores_gemma":[0.9954781,0.0004490357,0.0009677388,0.0003793552,0.0003442743,0.0008214679,0.0004742452,0.00001866484,0.001067253],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002933776,"threshold_uncertainty_score":0.01218551,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1045544197205947,"score_gpt":0.3563742029108062,"score_spread":0.2518197831902116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}