{"id":"W4307441992","doi":"10.1371/journal.pgen.1010434","title":"Formation of benign tumors by stem cell deregulation","year":2022,"lang":"en","type":"review","venue":"PLoS Genetics","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Stem cell; Biology; Stem cell niche; Cell biology; Cellular differentiation; Niche; Cancer stem cell; Homeostasis; Cell growth; Cell; Adult stem cell; Progenitor cell; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009415495,0.0001946166,0.0009081035,0.0001173918,0.00003447445,0.000006895394,0.00009322555,0.00009670691,0.000366857],"category_scores_gemma":[0.0000038444,0.0001745069,0.0002628565,0.0002161442,0.00001759174,0.00001877084,0.00005174714,0.0001671652,0.00001244676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001565105,"about_ca_system_score_gemma":0.000202038,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000263047,"about_ca_topic_score_gemma":0.000001277214,"domain_scores_codex":[0.9986575,0.00006831207,0.0005690152,0.0001848378,0.0003778625,0.0001424778],"domain_scores_gemma":[0.9990533,0.00004595262,0.0004528404,0.0003295447,0.00004495505,0.00007343078],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000005535249,0.0001180745,0.000001487776,0.03544659,0.00006234524,0.000002159161,0.0000942988,0.000006627814,0.0001485542,0.000003534026,0.002831003,0.9612798],"study_design_scores_gemma":[0.0002119769,0.0001529466,2.633615e-7,0.001483915,0.002071417,0.00001471084,0.000048688,0.00009971263,0.005919596,0.000003009305,0.9898568,0.0001369208],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002191807,0.9971808,0.00009695987,0.000007222787,0.00009323887,0.000821956,0.0002024428,0.00001640442,0.001361785],"genre_scores_gemma":[0.0001829887,0.997758,0.0002991077,0.00002039962,0.00007728495,0.00007008004,0.000822916,0.00004962213,0.0007196047],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9870259,"threshold_uncertainty_score":0.7116183,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0874412454386675,"score_gpt":0.3016461778639009,"score_spread":0.2142049324252334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}