{"id":"W4307441992","doi":"10.1371/journal.pgen.1010434","title":"Formation of benign tumors by stem cell deregulation","year":2022,"lang":"en","type":"review","venue":"PLoS Genetics","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Stem cell; Biology; Stem cell niche; Cell biology; Cellular differentiation; Niche; Cancer stem cell; Homeostasis; Cell growth; Cell; Adult stem cell; Progenitor cell; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005468902,0.0008081144,0.001011485,0.00199491,0.0001989144,0.0007633574,0.0007358831,0.001041266,0.001530874],"category_scores_gemma":[0.0005045682,0.0002903435,0.0003947286,0.001194105,0.0009473094,0.0009925796,0.0006583526,0.001880212,0.001303215],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007808961,"about_ca_system_score_gemma":0.0006426733,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007446606,"about_ca_topic_score_gemma":0.001389288,"domain_scores_codex":[0.9998248,0.00002672098,0.00002135755,0.00004944368,0.00006029538,0.00001734872],"domain_scores_gemma":[0.9997644,0.0001097637,0.00003342502,0.0000119048,0.00005403074,0.00002662363],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008872401,0.00005556105,0.0002904679,0.009675071,0.00009454201,0.0004694624,0.0000571516,0.0006578284,0.005227648,0.01109111,0.02835152,0.943941],"study_design_scores_gemma":[0.00002570037,0.00009512952,0.0008554038,0.001564195,0.00008958162,0.003946572,0.00003451585,0.0001555765,0.003088549,0.003611455,0.9865095,0.00002391208],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001801531,0.9981863,0.0002334348,0.0002668,0.0001705365,0.000003510302,0.00001331472,0.00001127358,0.0009346512],"genre_scores_gemma":[0.001510759,0.9970326,0.000198148,0.0002953944,0.0001717726,0.000006380322,0.00003146194,0.000002862549,0.0007506019],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00199491,"threshold_uncertainty_score":0.005665839,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0874412454386675,"score_gpt":0.3016461778639009,"score_spread":0.2142049324252334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}