{"id":"W4307450117","doi":"10.1136/ijgc-2022-esgo.1019","title":"2022-LBA-414-ESGO Preliminary clinical outcome of ADP-A2M4CD8, a next-generation autologous T-cell receptor T-cell therapy, in patients with advanced epithelial ovarian cancer","year":2022,"lang":"en","type":"article","venue":"International Journal of Gynecological Cancer","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Ovarian cancer; Medicine; Leukapheresis; Internal medicine; Oncology; CD8; Cancer; Population; Immunotherapy; Chemotherapy; Immunology; Antigen; Gastroenterology; Biology; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003491349,0.0003110165,0.0005803588,0.0001664414,0.0001631369,0.0003897911,0.0001576941,0.0005008269,0.002044918],"category_scores_gemma":[0.0003249835,0.00009478808,0.0004369083,0.0001573177,0.0002958702,0.0002855569,0.000157898,0.000794065,0.0004388579],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002577846,"about_ca_system_score_gemma":0.0002865632,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006631526,"about_ca_topic_score_gemma":0.001433406,"domain_scores_codex":[0.9998969,0.00003658002,0.000005340734,0.00001297132,0.00001131912,0.00003687082],"domain_scores_gemma":[0.9998649,0.00003406693,0.00001101009,0.00001762548,0.00001037903,0.00006199427],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3152545,0.0236659,0.03449986,0.001097119,0.001058585,0.00451932,0.0005219004,0.007444358,0.2076277,0.0009334887,0.008244513,0.3951327],"study_design_scores_gemma":[0.04859155,0.6198582,0.2079384,0.0001197837,0.001629637,0.005773527,0.0004242763,0.00751154,0.07110933,0.0009651025,0.03599384,0.00008486615],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903119,0.0021835,0.0003372637,0.0003407987,0.0001082202,0.0001451559,0.0007073525,0.00004991263,0.005815811],"genre_scores_gemma":[0.995905,0.0005339148,0.0001847585,0.0002724479,0.0000497293,0.00006788955,0.001179004,0.000009083521,0.00179818],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002044918,"threshold_uncertainty_score":0.006840944,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0713958216413929,"score_gpt":0.3759185532703714,"score_spread":0.3045227316289785,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}