{"id":"W4307552294","doi":"10.3390/cancers14215259","title":"DGKα, Bridging Membrane Shape Changes with Specific Molecular Species of DAG/PA: Implications in Cancer and Immunosurveillance","year":2022,"lang":"en","type":"review","venue":"Cancers","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Health Sciences Centre","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Diacylglycerol kinase; Phosphatidic acid; Second messenger system; Biology; Signal transduction; Cell biology; Computational biology; Biochemistry; Protein kinase C; Membrane; Phospholipid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002425004,0.0007007041,0.0007255611,0.000828544,0.0002985146,0.001203703,0.0004738193,0.001060483,0.001866164],"category_scores_gemma":[0.0003092811,0.0002185671,0.0004020115,0.0006545541,0.0005132907,0.001184641,0.0005301986,0.001543187,0.001509848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008736274,"about_ca_system_score_gemma":0.0004694079,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003694787,"about_ca_topic_score_gemma":0.0005737154,"domain_scores_codex":[0.9998835,0.00002005706,0.00001401139,0.0000266488,0.00002861372,0.00002706665],"domain_scores_gemma":[0.9998667,0.00002624048,0.0000393608,0.000004899071,0.00003517495,0.00002764676],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006993859,0.0001364663,0.001493542,0.01826178,0.0001881534,0.001595971,0.0004056034,0.001940818,0.1540503,0.03487819,0.06692309,0.7194266],"study_design_scores_gemma":[0.00001717412,0.0002702936,0.002960909,0.000845816,0.0001202279,0.002842226,0.0002439949,0.0003589182,0.01741769,0.008792868,0.9660882,0.00004161727],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002295152,0.9923019,0.0009168075,0.001200769,0.001198964,0.00000771559,0.00005738447,0.0000253165,0.001995951],"genre_scores_gemma":[0.01485489,0.9787146,0.0005461036,0.0007654167,0.0008881661,0.00001303909,0.0001397043,0.000009383484,0.004068693],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001866164,"threshold_uncertainty_score":0.006338596,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06375884218985518,"score_gpt":0.3141039621567343,"score_spread":0.2503451199668791,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}