{"id":"W4307561128","doi":"10.1155/2022/2757101","title":"Sex-Related Effects of Adrenergic Drugs on Conditioned Pain Modulation: A Randomized Controlled Cross-Over Double-Blind Trial","year":2022,"lang":"en","type":"article","venue":"Pain Research and Management","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Intégré Universitaire de Santé et de Services Sociaux du Centre-Sud-de-l'Île-de-Montréal; Université de Sherbrooke","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Université de Sherbrooke","keywords":"Medicine; Placebo; Anesthesia; Cold pressor test; Heart rate; Randomized controlled trial; Esmolol; Blood pressure; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001765611,0.001119649,0.003400546,0.000473829,0.0006171242,0.000727835,0.0007751631,0.001937424,0.00841326],"category_scores_gemma":[0.002056313,0.0006207322,0.001306218,0.0005010634,0.001352777,0.0007058972,0.0003891605,0.001405249,0.0006971243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004136397,"about_ca_system_score_gemma":0.001153813,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005110533,"about_ca_topic_score_gemma":0.0008366669,"domain_scores_codex":[0.9989564,0.0005021578,0.0001144501,0.0001828351,0.0001122871,0.0001317676],"domain_scores_gemma":[0.9988229,0.00036276,0.0003174945,0.0001141616,0.00009945586,0.0002833134],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9796433,0.007091079,0.0003110614,0.0005490164,0.0004158517,0.00001660563,0.00002171915,0.00005341391,0.00235559,0.00005324475,0.00016214,0.009326974],"study_design_scores_gemma":[0.9361107,0.06064386,0.001838115,0.00003125934,0.0003388475,0.00001397471,0.00001014834,0.0001505204,0.0004730817,0.00005223404,0.0003268976,0.00001041967],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822506,0.007460082,0.0009317831,0.0003680019,0.0007092486,0.006048971,0.0007575072,0.0001066389,0.001367137],"genre_scores_gemma":[0.9748759,0.004809094,0.003329766,0.0008943834,0.001114271,0.01131426,0.0005170866,0.00003049789,0.003114718],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00841326,"threshold_uncertainty_score":0.02814513,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0328156575621722,"score_gpt":0.3640114168296071,"score_spread":0.3311957592674349,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}