{"id":"W4307581080","doi":"10.1212/wnl.0000000000201629","title":"Tumor Necrosis Factor α Blockers and the Risk of Multiple Sclerosis","year":2022,"lang":"en","type":"letter","venue":"Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Multiple sclerosis; Medicine; Inflammatory Bowel Diseases; Tumor necrosis factor alpha; Tumor necrosis factor α; Risk factor; Population; Tumor necrosis factors; Inflammatory bowel disease; Necrosis; Immunology; Internal medicine; Disease; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001302056,0.0003247274,0.001032633,0.0006062233,0.001417653,0.001248331,0.0005374408,0.01143325,0.003290235],"category_scores_gemma":[0.01276751,0.0002746921,0.0005011346,0.0006932215,0.0007018105,0.0008367948,0.0003578557,0.006226179,0.002923088],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001879325,"about_ca_system_score_gemma":0.001604165,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004883848,"about_ca_topic_score_gemma":0.006455961,"domain_scores_codex":[0.9984518,0.000710661,0.0001305816,0.0001055231,0.0004797708,0.0001216699],"domain_scores_gemma":[0.9951017,0.002626735,0.0005011414,0.000161488,0.0009859701,0.0006228163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006938114,0.0002414218,0.02787681,0.0002572379,0.0001439982,0.01654998,0.0002251151,0.0002440285,0.0007025443,0.003015598,0.891728,0.05832136],"study_design_scores_gemma":[0.001277447,0.0007490517,0.0494886,0.002444681,0.000345109,0.09886498,0.0009092056,0.004080575,0.0009101852,0.02347959,0.8173065,0.0001442042],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01127375,0.02353687,0.0001622041,0.9385496,0.01094307,0.00002183276,0.0001306583,0.00005265377,0.01532937],"genre_scores_gemma":[0.1654556,0.02213608,0.0006097454,0.6887877,0.106286,0.0001060457,0.0001835264,0.00004140613,0.01639403],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01143325,"threshold_uncertainty_score":0.01363546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0524576246975174,"score_gpt":0.2701516834244211,"score_spread":0.2176940587269037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}