{"id":"W4307630691","doi":"10.3390/pharmaceutics14112300","title":"Synthesis & Evaluation of Novel Mannosylated Neoglycolipids for Liposomal Delivery System Applications","year":2022,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Institut National de la Recherche Scientifique; Health Sciences North; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Liposome; Delivery system; Chemistry; Pharmaceutical technology; Chromatography; Biochemistry; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002350477,0.0003975184,0.0001775793,0.0002380475,0.0001325909,0.0002700005,0.0001649091,0.0002927769,0.0007953236],"category_scores_gemma":[0.0001928662,0.0001142487,0.0002075159,0.0001470666,0.000146078,0.0003218824,0.000227302,0.0002384833,0.0003080889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003169943,"about_ca_system_score_gemma":0.0001948538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004132033,"about_ca_topic_score_gemma":0.0005684642,"domain_scores_codex":[0.999892,0.00001400866,0.00001616206,0.00002295817,0.00003736348,0.00001753139],"domain_scores_gemma":[0.9999142,0.00001169956,0.00002592994,0.000008362872,0.00002654688,0.00001325165],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003807363,0.00002144192,0.00004229058,0.00006492442,0.00000253527,0.00002979109,0.00001211074,0.0001160267,0.9975175,0.00006079932,0.00002059422,0.002073948],"study_design_scores_gemma":[0.000004236304,0.0001746629,0.0001918713,0.000002600977,0.000005007803,0.00002567948,0.000004607086,0.0003583051,0.9982386,0.000007322282,0.0009848718,0.000002316403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797173,0.002579436,0.01351546,0.00009763965,0.00004177619,0.0004002998,0.0004377118,0.0001175146,0.003092805],"genre_scores_gemma":[0.9738787,0.002032266,0.02048756,0.00005834003,0.00001128809,0.0002464868,0.0004061901,0.00003645086,0.002842607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007953236,"threshold_uncertainty_score":0.002660632,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09096818590438221,"score_gpt":0.3570117960206744,"score_spread":0.2660436101162922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}