{"id":"W4307630691","doi":"10.3390/pharmaceutics14112300","title":"Synthesis & Evaluation of Novel Mannosylated Neoglycolipids for Liposomal Delivery System Applications","year":2022,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Institut National de la Recherche Scientifique; Health Sciences North; Université du Québec à Montréal","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Liposome; Delivery system; Chemistry; Pharmaceutical technology; Chromatography; Biochemistry; Pharmacology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000510461,0.0001082717,0.0001206017,0.00005970974,0.0001620464,0.000009029355,0.0002371663,0.00005314289,0.00004642468],"category_scores_gemma":[0.00003395988,0.0001231323,0.0001063591,0.0001150883,0.00003007178,0.000003412117,0.0001314068,0.00006794612,0.000005097681],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006268268,"about_ca_system_score_gemma":0.000133357,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009366905,"about_ca_topic_score_gemma":0.000005025616,"domain_scores_codex":[0.9990094,0.00008098972,0.0002462047,0.0002416142,0.0002575871,0.0001642431],"domain_scores_gemma":[0.99914,0.00002942409,0.0001359233,0.0002705811,0.000377765,0.00004635061],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002055451,0.0002063366,0.0002053058,0.00009602108,0.0001620951,1.128877e-7,0.00004363746,0.008537123,0.9772312,0.0001265216,0.001632029,0.01155408],"study_design_scores_gemma":[0.001173492,0.0001387613,0.0001005019,0.00001314666,0.0004837211,0.00002368255,0.0003405985,0.05068842,0.7704041,0.00001430947,0.1763958,0.0002235049],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9793675,0.001086406,0.01680461,0.00007417165,0.0003518413,0.001072988,0.0005943423,0.00002204639,0.0006261021],"genre_scores_gemma":[0.9967676,0.00005810235,0.0009161494,0.0001284955,0.0001860855,0.001434253,0.000305752,0.00002043298,0.0001830723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2068271,"threshold_uncertainty_score":0.5021188,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09096818590438221,"score_gpt":0.3570117960206744,"score_spread":0.2660436101162922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}