{"id":"W4307658721","doi":"10.1002/iub.2688","title":"<scp>MiR</scp>‐548k suppresses apoptosis in breast cancer cells by affecting <scp>PTEN</scp>/<scp>PI3K</scp>/<scp>AKT</scp> signaling pathway","year":2022,"lang":"en","type":"article","venue":"IUBMB Life","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill Genome Centre; McGill University Health Centre","funders":"Shahrekord University of Medical Sciences","keywords":"PTEN; Breast cancer; PI3K/AKT/mTOR pathway; Protein kinase B; Cancer research; Apoptosis; microRNA; Cancer; Signal transduction; Biology; Medicine; Internal medicine; Cell biology; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002031566,0.0004260899,0.0005178154,0.0003057664,0.0003101734,0.0003848906,0.0002398427,0.0003595947,0.001806536],"category_scores_gemma":[0.000228804,0.0002111935,0.0005707886,0.0002528688,0.0002723991,0.0001873876,0.000211451,0.0008667429,0.0009026719],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003945087,"about_ca_system_score_gemma":0.0003874202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007510401,"about_ca_topic_score_gemma":0.0009647061,"domain_scores_codex":[0.9997527,0.00003383059,0.00003334881,0.00004406917,0.00008597422,0.00005014301],"domain_scores_gemma":[0.9999297,0.00001102806,0.00002332784,0.00001167754,0.00001277978,0.00001146857],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005105672,0.0001093802,0.0007448675,0.0001594066,0.00004302639,0.000118436,0.00002677798,0.0003991763,0.9908059,0.0001908908,0.0005146592,0.006376967],"study_design_scores_gemma":[0.00007116669,0.0005651985,0.005877451,0.00001675043,0.00009835295,0.0005440862,0.00004435665,0.002810929,0.979744,0.0001174311,0.01009427,0.00001612359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9851209,0.004939667,0.003408339,0.0004222118,0.0002009079,0.00007752695,0.0009835934,0.0005119737,0.004334806],"genre_scores_gemma":[0.9915073,0.001822922,0.002889052,0.0002053357,0.00002112994,0.00008254416,0.001010026,0.00004995892,0.002411661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001806536,"threshold_uncertainty_score":0.006043434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00820218146282394,"score_gpt":0.228260271205862,"score_spread":0.220058089743038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}