{"id":"W4307659329","doi":"10.1016/j.scitotenv.2022.159747","title":"Gestational exposure to perfluoroalkyl substances is associated with placental DNA methylation and birth size","year":2022,"lang":"en","type":"article","venue":"The Science of The Total Environment","topic":"Per- and polyfluoroalkyl substances research","field":"Environmental Science","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Ministry of Science and Technology of the People's Republic of China; National Natural Science Foundation of China; Health and Family Planning Commission of Sichuan Province; Shanghai Municipal Health Commission","keywords":"Methylation; DNA methylation; CpG site; Offspring; Fetus; Placenta; Internal medicine; Biology; Endocrinology; Pregnancy; Andrology; Genetics; Medicine; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003446515,0.0003008102,0.0002833393,0.0007080737,0.0002426558,0.0004913477,0.0003815108,0.0005933981,0.003652254],"category_scores_gemma":[0.002717693,0.0004608549,0.0005142468,0.0006818827,0.0002865632,0.0002556762,0.0003559749,0.0006218493,0.000288942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003216836,"about_ca_system_score_gemma":0.0002948095,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007327123,"about_ca_topic_score_gemma":0.004663956,"domain_scores_codex":[0.9996333,0.0001049143,0.00002361524,0.0001074978,0.0000639059,0.00006679969],"domain_scores_gemma":[0.9977137,0.0007185538,0.001029509,0.0002240044,0.0001030775,0.0002111632],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001164852,0.00009496886,0.9719005,0.00004306321,0.0002764156,0.0003611585,0.000341528,0.00008900908,0.01845639,0.0001499117,0.0001220929,0.007000135],"study_design_scores_gemma":[0.000004365295,0.0001048253,0.9979801,0.000008522952,0.00005251551,0.0002817175,0.00007810512,0.0001257352,0.001067704,0.00006960706,0.0002226636,0.000004086959],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974244,0.00100814,0.0002937148,0.0001208943,0.00001687989,0.00000259944,0.0003480941,0.00001663893,0.0007687482],"genre_scores_gemma":[0.9974961,0.0005251353,0.000254175,0.0000279948,0.00001228849,0.000007587234,0.0001696225,0.000009938065,0.001497231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007327123,"threshold_uncertainty_score":0.01456892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0104281459770732,"score_gpt":0.2215721952194066,"score_spread":0.2111440492423334,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}