{"id":"W4307743190","doi":"10.1182/blood.2022017079","title":"Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia","year":2022,"lang":"en","type":"article","venue":"Blood","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; Terry Fox Research Institute","funders":"","keywords":"Cancer research; Leukemia; Biology; Minimal residual disease; Stem cell; Cell cycle; Cell; Cell biology; Immunology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006917465,0.0001902491,0.0001881525,0.0002314356,0.000130836,0.0002748221,0.00006051575,0.000115138,0.001281434],"category_scores_gemma":[0.0000971042,0.00009821256,0.0001883887,0.0001816327,0.0001202045,0.0001647616,0.0002142494,0.0003083146,0.0002649538],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002372864,"about_ca_system_score_gemma":0.0001535655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003673412,"about_ca_topic_score_gemma":0.0006272987,"domain_scores_codex":[0.999925,0.00000838303,0.000006501148,0.00001354609,0.00001870581,0.00002781051],"domain_scores_gemma":[0.9999406,0.000007546978,0.00001784629,0.000004630539,0.000005373922,0.00002396296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009318114,0.00001554179,0.0009883727,0.00002235298,0.000002943251,0.00005452673,0.00001564978,0.0000253509,0.99796,0.00005216505,0.00002944016,0.0007405341],"study_design_scores_gemma":[0.00004316986,0.0004558778,0.08895258,0.00001231086,0.00003781471,0.0009162735,0.0001392978,0.001176167,0.9032734,0.0001947507,0.004790715,0.000007633162],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975016,0.001238265,0.0004956579,0.00003653651,0.000007647214,0.000009358792,0.0001661999,0.00004311055,0.0005017261],"genre_scores_gemma":[0.998055,0.0005796012,0.0003610376,0.00002882111,0.000005532054,0.00001067249,0.0003327754,0.000008646539,0.0006180599],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001281434,"threshold_uncertainty_score":0.004286826,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01706552378939415,"score_gpt":0.2796340491265029,"score_spread":0.2625685253371088,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}