{"id":"W4307763943","doi":"10.20944/preprints202210.0459.v1","title":"Phenylbenzohydrazides Obtained from Isatoic Anhydride Present Anti-Inflammatory Activity <em>in Vivo</em> and <em>in Vitro</em>","year":2022,"lang":"en","type":"preprint","venue":"Preprints.org","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Discovery Air (Canada)","funders":"Fundação Oswaldo Cruz","keywords":"In vivo; In vitro; Extravasation; Nitric oxide; Pharmacology; Chemistry; Dexamethasone; Inflammation; Nitric oxide synthase; Tumor necrosis factor alpha; Biochemistry; Immunology; Medicine; Biology; Internal medicine; Biotechnology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001364795,0.0004545527,0.0001840318,0.0002361991,0.0001329201,0.0001554975,0.0001692758,0.0001934349,0.005582248],"category_scores_gemma":[0.000127702,0.000106099,0.0002313683,0.0002101015,0.000187654,0.0001791434,0.0001083147,0.0004306162,0.001951915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002387237,"about_ca_system_score_gemma":0.0002416849,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003388445,"about_ca_topic_score_gemma":0.0005360035,"domain_scores_codex":[0.9999272,0.0000127564,0.000004393385,0.00001198631,0.00001966462,0.00002402398],"domain_scores_gemma":[0.9998969,0.00001315701,0.00004161378,0.00001106801,0.00001810272,0.00001912673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001886979,0.00003975206,0.0001994395,0.000258074,0.00001250081,0.00009255757,0.00001586799,0.0001584051,0.9936573,0.000248413,0.0001432852,0.004985634],"study_design_scores_gemma":[0.00003158685,0.0005264683,0.001559949,0.00001310088,0.00001658466,0.0002262032,0.00001163115,0.0001266025,0.9899499,0.00005365382,0.007478899,0.000005229956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.937753,0.01405365,0.02281721,0.0007299873,0.0002781582,0.000223818,0.001408328,0.000389076,0.02234678],"genre_scores_gemma":[0.969969,0.007941203,0.008963527,0.0001653291,0.0001278994,0.00006811032,0.001569879,0.00007837059,0.01111669],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005582248,"threshold_uncertainty_score":0.01867449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04476002237730802,"score_gpt":0.279794863173522,"score_spread":0.235034840796214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}