{"id":"W4307827212","doi":"10.1038/s41390-022-02289-0","title":"Functional response to a microbial synbiotic in the gastrointestinal system of children: a randomized clinical trial","year":2022,"lang":"en","type":"article","venue":"Pediatric Research","topic":"Gastrointestinal motility and disorders","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"","keywords":"Placebo; Probiotic; Medicine; Randomized controlled trial; Population; Internal medicine; Microbiome; Gut flora; Feces; Gastroenterology; Biology; Immunology; Bioinformatics; Microbiology; Environmental health; Bacteria; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003585842,0.00160686,0.003991376,0.0005547135,0.0006569655,0.001348143,0.0009621342,0.003342569,0.008194774],"category_scores_gemma":[0.005150743,0.0006891415,0.002967361,0.0006940075,0.001582421,0.001212207,0.0006413436,0.002534182,0.0007215043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00107364,"about_ca_system_score_gemma":0.001907998,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008715131,"about_ca_topic_score_gemma":0.001399568,"domain_scores_codex":[0.9979469,0.00121003,0.00018067,0.0003203999,0.0001494678,0.000192509],"domain_scores_gemma":[0.9967457,0.001111462,0.001073064,0.0002015902,0.0002189861,0.0006491136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9839798,0.003748173,0.0009647204,0.00138626,0.001417268,0.00003686223,0.00004329322,0.0001188737,0.0006445666,0.00008143781,0.000349936,0.007228869],"study_design_scores_gemma":[0.9251019,0.07061528,0.00224189,0.000144721,0.0009411915,0.00003145319,0.00003010078,0.0001577626,0.0001644848,0.0001015612,0.0004568118,0.00001278373],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9634275,0.01449167,0.001005319,0.001803714,0.001143469,0.01441899,0.001888919,0.0001496732,0.001670768],"genre_scores_gemma":[0.9563224,0.006413648,0.004103879,0.001868721,0.0009468278,0.02725601,0.001121202,0.00002526215,0.001942022],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008194774,"threshold_uncertainty_score":0.02741426,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09383408652511484,"score_gpt":0.3905742732482474,"score_spread":0.2967401867231326,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}