{"id":"W4307869026","doi":"10.3390/microorganisms10112163","title":"Linking Puberty and the Gut Microbiome to the Pathogenesis of Neurodegenerative Disorders","year":2022,"lang":"en","type":"review","venue":"Microorganisms","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Microbiome; Dysbiosis; Neurodegeneration; Gut–brain axis; Immune system; Pathogenesis; Neuroscience; Biology; Stressor; Immunology; Disease; Medicine; Bioinformatics; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004846324,0.0004836988,0.0009929525,0.0001655094,0.0006735387,0.0001376987,0.001394891,0.0001237347,0.0002379679],"category_scores_gemma":[0.0003607338,0.0002530465,0.0004091464,0.001142336,0.0005315735,0.00005034219,0.0009642983,0.0004681524,0.00005099708],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004551619,"about_ca_system_score_gemma":0.0001532724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002869788,"about_ca_topic_score_gemma":0.00005242986,"domain_scores_codex":[0.9967672,0.001188284,0.0005622938,0.0008092236,0.0002743367,0.0003986983],"domain_scores_gemma":[0.9976581,0.001131874,0.0003675451,0.0007572546,0.00001617043,0.00006905202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002224698,0.00007796285,8.074706e-7,0.001408622,0.00004483391,0.000006480319,0.002173379,0.00000431424,0.07454193,0.001117137,0.001351956,0.9192503],"study_design_scores_gemma":[0.0003302922,0.0000450123,0.000005624025,0.0002262529,0.0001376524,0.00005683641,0.0001251957,0.00000138139,0.003549795,0.0001310719,0.9950827,0.0003081309],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005061472,0.9949666,0.00008051794,0.00117657,0.0005787358,0.001971996,0.0003193384,0.00005139027,0.0003486652],"genre_scores_gemma":[0.0004836977,0.9963421,0.00008428711,0.002103643,0.00007912803,0.0001816735,0.00002394382,0.0001059246,0.0005955505],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9937308,"threshold_uncertainty_score":0.9999922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03462519581426154,"score_gpt":0.2682554269144037,"score_spread":0.2336302311001422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}