{"id":"W4307922435","doi":"10.1128/msphere.00446-22","title":"Probiotic Bifidobacteria Mitigate the Deleterious Effects of <i>para</i> -Cresol in a Drosophila melanogaster Toxicity Model","year":2022,"lang":"en","type":"article","venue":"mSphere","topic":"Complementary and Alternative Medicine Studies","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Probiotic; Gut flora; Biology; Microbiology; Bifidobacterium; Toxicity; Dysbiosis; Kidney disease; Pharmacology; Lactobacillus; Bacteria; Medicine; Internal medicine; Immunology; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002098221,0.0005089486,0.0003552822,0.0005667963,0.000351015,0.0003990554,0.0003890318,0.00068503,0.002528425],"category_scores_gemma":[0.0001783043,0.0002140181,0.0006080081,0.0001937901,0.0002643011,0.0003536762,0.0003508278,0.001351233,0.0003571986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004785884,"about_ca_system_score_gemma":0.0004915955,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003927346,"about_ca_topic_score_gemma":0.007316715,"domain_scores_codex":[0.9998106,0.00003047857,0.00002075055,0.00004517544,0.00005122511,0.00004172475],"domain_scores_gemma":[0.999786,0.00002169165,0.0000607435,0.00002047587,0.00003516868,0.00007597356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001011303,0.0003140573,0.001042375,0.0002088759,0.00004459413,0.0001971744,0.00007138128,0.0002736256,0.9913061,0.0004849875,0.0005700651,0.004475469],"study_design_scores_gemma":[0.0001939243,0.004612485,0.01969273,0.0001595818,0.0002290489,0.0004214912,0.0003159856,0.003505714,0.9579183,0.0005133049,0.01237897,0.00005835789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844811,0.002737414,0.003090814,0.000728461,0.0001927378,0.0001090844,0.003546192,0.0002291726,0.004885046],"genre_scores_gemma":[0.9784817,0.002646564,0.003895381,0.0003883779,0.00001991519,0.0001538067,0.001751543,0.00005785078,0.0126048],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003927346,"threshold_uncertainty_score":0.008458436,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01938528243608289,"score_gpt":0.268074337672721,"score_spread":0.2486890552366381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}