{"id":"W4307970687","doi":"10.3389/fmicb.2022.1021021","title":"BosR: A novel biofilm-specific regulator in Pseudomonas aeruginosa","year":2022,"lang":"en","type":"article","venue":"Frontiers in Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of British Columbia","funders":"University of British Columbia Graduate School; Canadian Institutes of Health Research; Centre for Blood Research, University of British Columbia; Fundación Ramón Areces; University of British Columbia; Canada Research Chairs; Natural Sciences and Engineering Research Council of Canada; Cystic Fibrosis Canada","keywords":"Biofilm; Pseudomonas aeruginosa; Response regulator; Biology; Regulator; Mutant; Gene; Transposable element; Phenotype; Transcriptional regulation; Microbiology; Two-component regulatory system; Transposon mutagenesis; Cell biology; Genetics; Transcription factor; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002653729,0.0006928784,0.0006429416,0.0003644323,0.0002420408,0.0003952088,0.0002918324,0.0004334798,0.0008932775],"category_scores_gemma":[0.0002318626,0.0001603323,0.0004477004,0.000274805,0.0003227613,0.0002404656,0.000366262,0.0006462501,0.0007751159],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004463543,"about_ca_system_score_gemma":0.000398777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00108822,"about_ca_topic_score_gemma":0.001124622,"domain_scores_codex":[0.9997712,0.00003195119,0.00001571528,0.00005654883,0.00009376425,0.000030832],"domain_scores_gemma":[0.9998633,0.00002923608,0.00004134249,0.00001347095,0.00002169403,0.00003091252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004394979,0.00001618293,0.0002040608,0.0000489384,0.000002420394,0.0001039797,0.000006833331,0.00004651573,0.997917,0.00004106299,0.00003990748,0.001529255],"study_design_scores_gemma":[0.00003820395,0.0005834756,0.02149435,0.00002735041,0.00006040142,0.002113502,0.00008152999,0.003448158,0.9632544,0.0001531791,0.008710376,0.00003503372],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9660503,0.008566345,0.01746812,0.0006586906,0.0001469461,0.000168736,0.002349798,0.0009719501,0.003619033],"genre_scores_gemma":[0.9760552,0.002014091,0.01390604,0.0004109028,0.00008113664,0.00007946418,0.003275665,0.0001366077,0.004041018],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00108822,"threshold_uncertainty_score":0.003238499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007353820409711897,"score_gpt":0.2005577143632717,"score_spread":0.1932038939535598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}