{"id":"W4307999814","doi":"10.1101/2022.11.01.514384","title":"Dlg5 and Cadherins are key to peripheral glia integrity","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; National Institutes of Health","keywords":"PDZ domain; Septate junctions; Adherens junction; Gene knockdown; Cadherin; Cell biology; Tight junction; Biology; Gap junction; Cell; Cell culture; Genetics; Intracellular","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004806399,0.000281947,0.0001992035,0.0001802262,0.0002475728,0.0003633636,0.0001979334,0.0003833336,0.001326231],"category_scores_gemma":[0.00006437777,0.0001215977,0.0001701611,0.0001019423,0.0002980678,0.0002289332,0.0003472216,0.0003776401,0.0003324483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004267455,"about_ca_system_score_gemma":0.0001881143,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001299895,"about_ca_topic_score_gemma":0.002521447,"domain_scores_codex":[0.999895,0.000007628676,0.000008622768,0.00002905689,0.00003199768,0.00002780956],"domain_scores_gemma":[0.9999201,0.000004815212,0.00002624226,0.000005941561,0.00001108143,0.00003175647],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003445517,0.00000631795,0.0006785516,0.00004346972,0.000003828272,0.00008872324,0.0000102584,0.00004701122,0.9977308,0.0002001729,0.00005506314,0.001101403],"study_design_scores_gemma":[0.00001573239,0.0001396583,0.06371443,0.0000257321,0.00003358109,0.0007248969,0.000131326,0.001999229,0.9253541,0.0001864331,0.007667607,0.000007258093],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915068,0.00235326,0.00274977,0.0001597209,0.00002399421,0.00001804015,0.0004422949,0.0001233247,0.002622885],"genre_scores_gemma":[0.9961135,0.0002689798,0.001020298,0.0000613886,0.000002329663,0.000006175822,0.0003057467,0.000008077407,0.002213408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001326231,"threshold_uncertainty_score":0.004436672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01491236051149047,"score_gpt":0.2324780397254303,"score_spread":0.2175656792139398,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}