{"id":"W4308010362","doi":"10.33425/2689-1069.1042","title":"Cardiotoxicity: Role of Sacubitril-Valsartan in Heart Failure with Reduced Ejection Fraction and Cancer with Hepatic Metastasis","year":2022,"lang":"en","type":"article","venue":"Clinical Reviews & Cases","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cascades (Canada)","funders":"","keywords":"Sacubitril; Sacubitril, Valsartan; Valsartan; Medicine; Ejection fraction; Heart failure; Colorectal cancer; Cardiotoxicity; Tolerability; Cardiology; Internal medicine; Metastasis; Cancer; Oncology; Chemotherapy; Blood pressure; Adverse effect","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001894311,0.0003092348,0.0003039979,0.0002844002,0.0003424948,0.000383374,0.0001621014,0.0005584408,0.0008769129],"category_scores_gemma":[0.0004463805,0.00008001381,0.0003345805,0.0001467808,0.0002911029,0.0002037016,0.0002604371,0.0006882026,0.0001929655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002577851,"about_ca_system_score_gemma":0.0002209541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003170067,"about_ca_topic_score_gemma":0.0006943363,"domain_scores_codex":[0.9998996,0.00003473878,0.00001180427,0.00001417067,0.00001578357,0.00002395167],"domain_scores_gemma":[0.9997765,0.00008511542,0.00007052341,0.00001465785,0.00001638928,0.00003673775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001265655,0.0003071795,0.08813055,0.0007179937,0.0001732544,0.7586879,0.0005368578,0.000773067,0.03706065,0.002130671,0.001706877,0.1085093],"study_design_scores_gemma":[0.0001179802,0.001780182,0.06125128,0.0002539187,0.0003024605,0.892333,0.0002990179,0.00128024,0.01532668,0.001213289,0.02580646,0.00003536258],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.8701236,0.1028619,0.004533741,0.004314112,0.0002586067,0.0001186522,0.00008176812,0.00009963577,0.0176079],"genre_scores_gemma":[0.9857879,0.01092768,0.0008431093,0.0007632204,0.0004495483,0.000009687572,0.00004940258,0.00001018967,0.001159387],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0008769129,"threshold_uncertainty_score":0.002933562,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05069883566726317,"score_gpt":0.369521041399733,"score_spread":0.3188222057324698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}