{"id":"W4308022925","doi":"10.1101/2022.11.01.514688","title":"RNA-mediated double-strand break repair in human cells","year":2022,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Biology; Homologous recombination; DNA; RNA; Non-homologous end joining; DNA repair; Transcription (linguistics); Gene; Genetics; DNA damage; Cell biology; Molecular biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368167,0.0002873972,0.0002601755,0.0002850373,0.0001517616,0.0003606861,0.0001415884,0.0003217551,0.003203767],"category_scores_gemma":[0.0001840653,0.0001093104,0.0001739739,0.0002241191,0.0001599017,0.0001176167,0.0002156665,0.0002467673,0.003462744],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002376795,"about_ca_system_score_gemma":0.0001905583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002986436,"about_ca_topic_score_gemma":0.0001572234,"domain_scores_codex":[0.9998178,0.00004302689,0.00001102727,0.0000477453,0.00006540545,0.00001495254],"domain_scores_gemma":[0.9999439,0.0000171819,0.000009313405,0.00001269829,0.00001050818,0.000006484132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002279276,0.00004201509,0.0006179003,0.0004122762,0.00002500411,0.000572765,0.00009609428,0.0009327827,0.9525379,0.006062146,0.003034814,0.03543847],"study_design_scores_gemma":[0.00005124318,0.0004312861,0.004527858,0.00005640487,0.0000413383,0.002441245,0.00004874383,0.002788615,0.8648506,0.003720291,0.1210281,0.00001432663],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4663342,0.09968375,0.3010998,0.001760774,0.001758969,0.0006427275,0.01308345,0.005615822,0.1100206],"genre_scores_gemma":[0.8521642,0.02102448,0.0791728,0.0004082682,0.0002577913,0.0003481416,0.01144573,0.0002628583,0.03491572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003203767,"threshold_uncertainty_score":0.01071769,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119514649220424,"score_gpt":0.2265425496559632,"score_spread":0.2153474031637589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}