{"id":"W4308026284","doi":"10.1001/jamanetworkopen.2022.39884","title":"Participation of Patients From Racial and Ethnic Minority Groups in Phase 1 Early Cancer Drug Development Trials in the US, 2000-2018","year":2022,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Ethics in Clinical Research","field":"Medicine","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute","keywords":"Ethnic group; Medicine; Pacific islanders; Clinical trial; Demography; Cancer; Gerontology; Health equity; Internal medicine; Public health; Population; Environmental health; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.01028472,0.0001801248,0.0003018887,0.0008804279,0.0006476649,0.0007769153,0.0005373394,0.0004773367,0.002391348],"category_scores_gemma":[0.02393061,0.000248286,0.0003634556,0.001732395,0.0004698184,0.001154252,0.0007492283,0.0007424049,0.0004108429],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006927711,"about_ca_system_score_gemma":0.001862771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002585475,"about_ca_topic_score_gemma":0.007639748,"domain_scores_codex":[0.9898325,0.005721424,0.001332802,0.001000182,0.001702349,0.000410745],"domain_scores_gemma":[0.975318,0.005531409,0.01603763,0.000726881,0.001386056,0.001000067],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002054959,0.0002347367,0.9690503,0.0002910078,0.000204056,0.00003275293,0.0004488001,0.00007792509,0.0003514318,0.0002291145,0.004283067,0.02274195],"study_design_scores_gemma":[0.0004480415,0.001059343,0.9841286,0.000397303,0.0002550486,0.0002899582,0.0006527547,0.0003832979,0.000646982,0.0003068439,0.01141498,0.00001680344],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9687338,0.007361525,0.000870457,0.004199245,0.0001249171,0.0007160648,0.009302224,0.00003071979,0.008661032],"genre_scores_gemma":[0.9892817,0.001667268,0.0009227917,0.002424869,0.0001846493,0.001061351,0.003347445,0.0000133972,0.001096509],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9995227,"threshold_uncertainty_score":0.05439144,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.4469637731990482,"score_gpt":0.5666021790851875,"score_spread":0.1196384058861393,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}