{"id":"W4308029396","doi":"10.1016/j.shj.2022.100102","title":"Clinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future","year":2022,"lang":"en","type":"review","venue":"Structural Heart","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; University of British Columbia","funders":"National Heart, Lung, and Blood Institute; Boston Scientific Corporation; National Institutes of Health; Abiomed; Irving Medical Center, Columbia University; Edwards Lifesciences","keywords":"Bicuspid aortic valve; Valve replacement; Medicine; Observational study; Randomized controlled trial; Clinical trial; valvular heart disease; Aortic valve replacement; Population; Multidisciplinary approach; Clinical equipoise; Aortic valve; Intensive care medicine; Heart valve; Cardiology; Internal medicine; Stenosis; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001307972,0.0006028101,0.001747265,0.0001655899,0.0006359491,0.00006505404,0.0002442394,0.0002372009,0.0001924915],"category_scores_gemma":[0.0001952843,0.0003487695,0.008209215,0.0001625927,0.0002035731,0.0000618957,0.0001214064,0.0007868015,0.000007737521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003168734,"about_ca_system_score_gemma":0.0005718101,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001083316,"about_ca_topic_score_gemma":0.000006313614,"domain_scores_codex":[0.9955657,0.0006161094,0.0009057264,0.00129953,0.0008333361,0.000779613],"domain_scores_gemma":[0.9960008,0.00162082,0.0001966506,0.00137807,0.0001455032,0.0006581651],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001070566,0.0001872056,0.0003229893,0.01153483,0.003875046,0.00000286283,0.00009939037,4.123555e-7,2.665691e-8,0.0005607462,0.001014507,0.9813314],"study_design_scores_gemma":[0.001707335,0.00268031,0.03703338,0.001473439,0.01145194,0.00002405945,0.0001943919,0.00003991663,4.851492e-8,0.0003154448,0.9447409,0.0003388234],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002338303,0.9841223,0.0000013154,0.0006679749,0.001385536,0.009839949,0.001535669,0.00005224781,0.00005670387],"genre_scores_gemma":[0.004639772,0.9863756,0.0001140903,0.0002412837,0.002609408,0.003717004,0.001741994,0.0001507909,0.0004100408],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9809926,"threshold_uncertainty_score":0.9998964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2736686599106454,"score_gpt":0.530768548378035,"score_spread":0.2570998884673896,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}