{"id":"W4308039542","doi":"10.1016/j.chom.2022.09.014","title":"Gut colonization by Proteobacteria alters host metabolism and modulates cocaine neurobehavioral responses","year":2022,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Tryptophan and brain disorders","field":"Neuroscience","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Concordia University; Université du Québec à Montréal","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Biology; Host (biology); Colonization; Proteobacteria; Metabolism; Microbiology; Bacteria; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006355382,0.0002097979,0.0002275524,0.000154494,0.0002149363,0.0002893418,0.0001055367,0.0003339999,0.001959645],"category_scores_gemma":[0.0001368597,0.0001397266,0.0001900738,0.00008045006,0.0002119436,0.0001601703,0.0002263959,0.0004753937,0.0002262427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003291894,"about_ca_system_score_gemma":0.0002444078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00161171,"about_ca_topic_score_gemma":0.004647814,"domain_scores_codex":[0.9998995,0.00001652543,0.000002700534,0.00002118488,0.00001201768,0.00004797139],"domain_scores_gemma":[0.9999459,0.000005104298,0.00001457603,0.000004261325,0.000007238361,0.00002291737],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00271265,0.0001656554,0.004800646,0.00002635354,0.00002565243,0.00009203878,0.00003329926,0.00005556234,0.9886053,0.00005840797,0.00007380883,0.003350506],"study_design_scores_gemma":[0.0001344793,0.004550519,0.4414939,0.00006477665,0.0001281397,0.0007232725,0.0009213632,0.002369053,0.5466568,0.0006087156,0.002314521,0.00003437956],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990761,0.0002080526,0.0001613737,0.00005892924,0.00001055877,0.000005564459,0.00009648954,0.000007232259,0.0003755859],"genre_scores_gemma":[0.9981987,0.0002579575,0.0002678197,0.00005995085,0.000004994039,0.00001412477,0.00009290684,0.000006184714,0.001097454],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001959645,"threshold_uncertainty_score":0.006555676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01360604318561298,"score_gpt":0.2354008248918308,"score_spread":0.2217947817062178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}