{"id":"W4308056077","doi":"10.1182/bloodadvances.2022007611","title":"Chronic GvHD NIH Consensus Project Biology Task Force: evolving path to personalized treatment of chronic GvHD","year":2022,"lang":"en","type":"article","venue":"Blood Advances","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"National Cancer Institute; Canadian Institutes of Health Research; Pharmacyclics; Genentech; Syndax Pharmaceuticals; National Institutes of Health; Incyte; Therakos; Florida Department of Health; Gilead Sciences; Amgen; National Heart, Lung, and Blood Institute; Pfizer; National Institute of Allergy and Infectious Diseases; Celgene; AstraZeneca; Eli Lilly and Company","keywords":"Disease; Medicine; Intensive care medicine; Hematopoietic stem cell transplantation; Consensus conference; Graft-versus-host disease; Perspective (graphical); Stem cell; Immunology; Bioinformatics; Pathology; Biology; Internal medicine; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000154984,0.0002305528,0.0005448771,0.0001689618,0.0001634626,0.000005868668,0.0001030433,0.00005299259,0.001030522],"category_scores_gemma":[0.00004087678,0.0001957442,0.000144719,0.0003219178,0.0001097466,0.00003424071,0.0000290004,0.00009838399,0.00001313229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004774127,"about_ca_system_score_gemma":0.0007031686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009782313,"about_ca_topic_score_gemma":0.00004063324,"domain_scores_codex":[0.99833,0.0001341825,0.000410906,0.0004371414,0.0002785593,0.0004092395],"domain_scores_gemma":[0.9991395,0.0002340668,0.0001670229,0.0002917334,0.00007147116,0.00009617912],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001384572,0.003134868,0.05367655,0.004995601,0.001589759,0.000943028,0.01555644,0.0006466547,0.772904,0.002415921,0.0004802581,0.1422724],"study_design_scores_gemma":[0.06829346,0.07140027,0.01587148,0.0009174507,0.004383901,0.003405852,0.01231739,0.00182094,0.4893337,0.0006024185,0.329574,0.002079113],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9255028,0.06478775,0.0004655126,0.0006337291,0.0006213927,0.003053074,0.0003807473,0.000155609,0.004399367],"genre_scores_gemma":[0.9939491,0.001036075,0.002678974,0.00006906767,0.0002056274,0.0005072795,0.000160152,0.0000362172,0.001357464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3290938,"threshold_uncertainty_score":0.9998827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01962665067547011,"score_gpt":0.3082489974875755,"score_spread":0.2886223468121054,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}