{"id":"W4308075637","doi":"10.1088/1758-5090/ac9ff4","title":"Bioscaffold developed with decellularized human amniotic membrane seeded with mesenchymal stromal cells: assessment of efficacy and safety profiles in a second-degree burn preclinical model","year":2022,"lang":"en","type":"article","venue":"Biofabrication","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Decellularization; Mesenchymal stem cell; Biomedical engineering; Stromal cell; Materials science; Regenerative medicine; Membrane; Third-Degree Burn; Amnion; Medicine; Tissue engineering; Pathology; Surgery; Cell biology; Chemistry; Stem cell; Fetus; Biology; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003188006,0.0003302308,0.0001748622,0.0002620459,0.0001124879,0.0001883043,0.0001190321,0.0002907521,0.0004306283],"category_scores_gemma":[0.0001656635,0.00008739609,0.0002517181,0.0001457142,0.0001544685,0.0001913869,0.0001200008,0.0002476091,0.0001070294],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001354961,"about_ca_system_score_gemma":0.0001445187,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000475499,"about_ca_topic_score_gemma":0.000407846,"domain_scores_codex":[0.9998846,0.00001719606,0.00001038361,0.00002233117,0.00004760617,0.0000179468],"domain_scores_gemma":[0.9998608,0.00002634647,0.00004706662,0.00001589076,0.00003009292,0.00001986181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003838104,0.0001915085,0.0003055798,0.00005999906,0.000008202154,0.00004819538,0.00002833355,0.0001870849,0.995454,0.00005305928,0.00002099117,0.003259309],"study_design_scores_gemma":[0.00001156736,0.002695919,0.001425719,0.000005593808,0.00002230188,0.00007032811,0.00002022595,0.0005863773,0.994482,0.00001443398,0.0006615832,0.000003966612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959454,0.001591042,0.001923402,0.00001827809,0.00003291632,0.00003711764,0.0000860726,0.00002477638,0.0003410935],"genre_scores_gemma":[0.995093,0.001144231,0.002592965,0.00001998312,0.00001135268,0.0000521063,0.0001202046,0.00000655813,0.000959586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000475499,"threshold_uncertainty_score":0.001685977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04309388302043816,"score_gpt":0.3097347403732146,"score_spread":0.2666408573527765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}