{"id":"W4308075637","doi":"10.1088/1758-5090/ac9ff4","title":"Bioscaffold developed with decellularized human amniotic membrane seeded with mesenchymal stromal cells: assessment of efficacy and safety profiles in a second-degree burn preclinical model","year":2022,"lang":"en","type":"article","venue":"Biofabrication","topic":"Tissue Engineering and Regenerative Medicine","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Coordenação de Aperfeiçoamento de Pessoal de Nível Superior","keywords":"Decellularization; Mesenchymal stem cell; Biomedical engineering; Stromal cell; Materials science; Regenerative medicine; Membrane; Third-Degree Burn; Amnion; Medicine; Tissue engineering; Pathology; Surgery; Cell biology; Chemistry; Stem cell; Fetus; Biology; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000436385,0.0001902362,0.000453704,0.0002024409,0.0001059541,0.000007379639,0.00008589632,0.00006166855,0.00006687227],"category_scores_gemma":[0.00002385319,0.0001344316,0.00002590641,0.0004042987,0.0001231027,0.00004148228,0.00005338044,0.00028158,3.784585e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000125106,"about_ca_system_score_gemma":0.0002652208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002377042,"about_ca_topic_score_gemma":0.00001720134,"domain_scores_codex":[0.9985135,0.00009419707,0.0004328887,0.0003682401,0.0003935929,0.0001976007],"domain_scores_gemma":[0.9992855,0.00007988191,0.0001794527,0.0002610994,0.00008329767,0.0001107224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007402434,0.0006856367,0.01656852,0.0002916614,0.0001337888,0.00002973893,0.0008367735,0.005338617,0.9739066,0.0006770439,0.00003165178,0.0007596994],"study_design_scores_gemma":[0.0245487,0.005845478,0.6889449,0.0004985735,0.0004163595,0.0001819839,0.0008612211,0.1552853,0.1222957,0.00001005391,0.0005107108,0.0006010892],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863629,0.0003124913,0.01160098,0.000484175,0.000035513,0.000944289,0.0000178118,0.00004970305,0.0001921489],"genre_scores_gemma":[0.9757811,0.00001477369,0.02262658,0.00001600748,0.00004235386,0.00008921027,0.0001490031,0.00002857763,0.001252352],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8516109,"threshold_uncertainty_score":0.5481962,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04309388302043816,"score_gpt":0.3097347403732146,"score_spread":0.2666408573527765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}