{"id":"W4308120819","doi":"10.3390/cells11213459","title":"Host Response of Human Epidermis to Methicillin-Resistant Staphylococcus aureus Biofilm Infection and Synthetic Antibiofilm Peptide Treatment","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Leids Universitair Medisch Centrum; Universiteit Leiden","keywords":"Biofilm; Microbiology; Staphylococcus aureus; Epidermis (zoology); Inflammation; Staphylococcal Skin Infections; Biology; Skin infection; Barrier function; Bacteria; Immunology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009219359,0.0001235837,0.0001630158,0.00007625656,0.00007789725,0.0001985373,0.00004344858,0.0001490667,0.001263563],"category_scores_gemma":[0.00008361619,0.00006497734,0.0001329622,0.00006587721,0.0001056488,0.0001133675,0.0001023723,0.0003055895,0.000143587],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007660012,"about_ca_system_score_gemma":0.00008446351,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001305462,"about_ca_topic_score_gemma":0.000167171,"domain_scores_codex":[0.9999222,0.0000168036,0.000004959817,0.00001989598,0.00002037305,0.00001575001],"domain_scores_gemma":[0.9999684,0.000007308542,0.000007007955,0.000003277116,0.000006255382,0.000007731766],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001468211,0.0000178855,0.0001906239,0.00003120209,0.000002441157,0.00002652735,0.00001462617,0.00003090101,0.9987003,0.00001148156,0.00001415963,0.000813054],"study_design_scores_gemma":[0.00001663649,0.001577056,0.01967215,0.00001250589,0.00002081661,0.0003064111,0.0001943691,0.0008064046,0.9753363,0.00005741174,0.001992603,0.00000743461],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960601,0.001745891,0.001044939,0.00004859837,0.00002848884,0.00002956345,0.0002310667,0.00001296563,0.0007983669],"genre_scores_gemma":[0.9963369,0.0008055507,0.001158318,0.00007012379,0.000008661588,0.00004027515,0.0002542379,0.000004738131,0.001321122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263563,"threshold_uncertainty_score":0.004227042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846140759969882,"score_gpt":0.2564421003235595,"score_spread":0.2379806927238607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}