{"id":"W4308120819","doi":"10.3390/cells11213459","title":"Host Response of Human Epidermis to Methicillin-Resistant Staphylococcus aureus Biofilm Infection and Synthetic Antibiofilm Peptide Treatment","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research; Leids Universitair Medisch Centrum; Universiteit Leiden","keywords":"Biofilm; Microbiology; Staphylococcus aureus; Epidermis (zoology); Inflammation; Staphylococcal Skin Infections; Biology; Skin infection; Barrier function; Bacteria; Immunology; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004844255,0.0002163639,0.0003971375,0.0002296561,0.0005344014,0.00001551515,0.0001130299,0.0001087604,0.0006462777],"category_scores_gemma":[0.00003948504,0.0001976842,0.000132065,0.0001634167,0.000246148,0.00004359219,0.0001657756,0.0001967318,0.00005526188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001256021,"about_ca_system_score_gemma":0.00006204718,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00175809,"about_ca_topic_score_gemma":0.00007969774,"domain_scores_codex":[0.9983826,0.0005770257,0.0003203625,0.0003599811,0.00004423385,0.0003158077],"domain_scores_gemma":[0.999149,0.0003040371,0.0001631168,0.0003097641,0.00003717944,0.00003687084],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008715782,0.0002305962,0.0004579717,0.00002565438,0.0001237471,0.00001140237,0.001007373,0.00005717556,0.9945261,0.0001452495,0.002016219,0.0005268973],"study_design_scores_gemma":[0.0006103478,0.001939648,0.005491875,0.0000272893,0.00007306106,0.000006789641,0.0006930924,0.000001217783,0.9612145,0.00002964061,0.02969986,0.0002126941],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976406,0.0006345237,0.00002600412,0.0002844135,0.0003023474,0.0003853026,0.0003686976,0.00004618925,0.0003119812],"genre_scores_gemma":[0.993599,0.0001043037,0.00007820487,0.0001600572,0.00001630596,0.00002431169,0.00003291015,0.00002306656,0.005961832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03331165,"threshold_uncertainty_score":0.8061327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01846140759969882,"score_gpt":0.2564421003235595,"score_spread":0.2379806927238607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}