{"id":"W4308123313","doi":"10.3390/nu14214594","title":"The Roles of MTRR and MTHFR Gene Polymorphisms in Colorectal Cancer Survival","year":2022,"lang":"en","type":"article","venue":"Nutrients","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto; Memorial University of Newfoundland","funders":"National Cancer Institute; National Natural Science Foundation of China","keywords":"MTRR; Methylenetetrahydrofolate reductase; Colorectal cancer; Medicine; Internal medicine; Single-nucleotide polymorphism; Proportional hazards model; Oncology; Allele; Genetics; MLH1; Genotype; Cancer; Biology; Gene; DNA mismatch repair","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001068257,0.0002615322,0.0002268538,0.0004357614,0.0002376446,0.0003786794,0.0002988809,0.0002754855,0.001299508],"category_scores_gemma":[0.002777863,0.0001243471,0.0004375396,0.0005772224,0.000368845,0.0001658657,0.0002831908,0.0004163918,0.0001491428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006066236,"about_ca_system_score_gemma":0.0005893217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02452969,"about_ca_topic_score_gemma":0.02899747,"domain_scores_codex":[0.9995151,0.0001605894,0.00002755582,0.0001313522,0.00007267112,0.00009278474],"domain_scores_gemma":[0.9978103,0.0007499616,0.0007713409,0.0002292982,0.0002012582,0.0002378463],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0005302123,0.00001259753,0.9909423,0.00002092397,0.000240735,0.00005917569,0.00007835768,0.0002992583,0.001840049,0.00005250812,0.0001623874,0.005761469],"study_design_scores_gemma":[0.000007514842,0.00005259312,0.9986345,0.000007109849,0.0001445778,0.00009852769,0.0000312259,0.0004401708,0.0002553027,0.00007306151,0.0002522569,0.000003180498],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969914,0.001630257,0.0002564211,0.0003126666,0.000006172158,0.00000251959,0.0004289828,0.00001004223,0.0003615644],"genre_scores_gemma":[0.9994679,0.0001666592,0.0001005165,0.00002004552,0.000005815913,0.00000158807,0.0001275474,0.000002366036,0.0001076214],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02452969,"threshold_uncertainty_score":0.04877383,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02544322350846198,"score_gpt":0.3104749957312386,"score_spread":0.2850317722227766,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}