{"id":"W4308132322","doi":"10.15690/vsp.v21i5.2452","title":"Filaggrin Defect at Atopic Dermatitis: Modern Treatment Options","year":2022,"lang":"en","type":"article","venue":"Вопросы современной педиатрии","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children’s Health Research Institute","funders":"","keywords":"Filaggrin; Atopic dermatitis; Dermatology; Medicine; Pathogenesis; Disease; Skin barrier; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001199108,0.0002936608,0.0004665291,0.0001813408,0.0007887761,0.0000203453,0.000178033,0.00009611129,0.005702782],"category_scores_gemma":[0.00004696112,0.0002733785,0.0004363174,0.0002494509,0.0001147347,0.00009271081,0.0002371139,0.0002309859,0.0006023024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005701114,"about_ca_system_score_gemma":0.0001962675,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004970809,"about_ca_topic_score_gemma":0.00004985982,"domain_scores_codex":[0.9980345,0.0002520128,0.0003758731,0.0004655483,0.0003780631,0.0004940084],"domain_scores_gemma":[0.9987622,0.00012792,0.0001078486,0.000668937,0.00004417853,0.0002888369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000482539,0.004820528,0.5615056,0.0003741656,0.00176504,0.005658277,0.00343347,0.001674055,0.00166434,0.00333936,0.3811253,0.03415737],"study_design_scores_gemma":[0.008458039,0.0009737144,0.4447054,0.00008264647,0.001242649,0.006756536,0.0005753171,0.003038828,0.002858735,0.003305705,0.5271264,0.0008760743],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9611195,0.008756682,0.0001839057,0.003692409,0.0005053761,0.0008630421,0.000234046,0.0004023743,0.0242427],"genre_scores_gemma":[0.9806616,0.0002281939,0.0003092238,0.002123761,0.0001144893,0.0006824991,0.0004191556,0.00004482795,0.01541625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1460011,"threshold_uncertainty_score":0.9999719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01824591600164013,"score_gpt":0.268871545581551,"score_spread":0.2506256295799109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}