{"id":"W4308179427","doi":"10.1371/journal.ppat.1010613","title":"HIV proviral genetic diversity, compartmentalization and inferred dynamics in lung and blood during long-term suppressive antiretroviral therapy","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; AIDS Vancouver; Simon Fraser University","funders":"National Institute of Neurological Disorders and Stroke; National Institute of Allergy and Infectious Diseases; National Heart, Lung, and Blood Institute; National Institute of Mental Health; National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research; National Institute on Drug Abuse; National Institutes of Health; Canada Research Chairs; National Institute on Aging; National Cancer Institute; Michael Smith Health Research BC","keywords":"Biology; Context (archaeology); Human immunodeficiency virus (HIV); Compartmentalization (fire protection); Lung; Genetic diversity; Genetics; Virology; Immunology; Evolutionary biology; Population; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00124761,0.0001581232,0.000388737,0.0008230233,0.0004292271,0.00108929,0.0003970081,0.0004131324,0.000606566],"category_scores_gemma":[0.005035807,0.0001969447,0.0001971873,0.0008092818,0.0004231207,0.0005676697,0.000542725,0.0005022874,0.0001831125],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003398645,"about_ca_system_score_gemma":0.0001892646,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002513215,"about_ca_topic_score_gemma":0.003111365,"domain_scores_codex":[0.9991072,0.0002984302,0.00005099622,0.0002971023,0.0001365507,0.0001097813],"domain_scores_gemma":[0.9978987,0.0009681617,0.0004534254,0.0002021358,0.0002882384,0.0001892704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009014438,0.00005944176,0.9420354,0.00005655293,0.000129972,0.0002600877,0.001563322,0.0008203349,0.0383364,0.0001742822,0.0001192368,0.01554353],"study_design_scores_gemma":[0.00002028244,0.0004409833,0.9780971,0.00003036535,0.0001061599,0.001446633,0.001275085,0.00825393,0.00893617,0.0006558725,0.0007032496,0.00003418199],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990233,0.0002090346,0.0004426029,0.00001417335,0.000001031167,0.000004452805,0.0001427939,0.000007402938,0.0001552018],"genre_scores_gemma":[0.9991253,0.00004540038,0.0005370271,0.00001679322,0.000003432998,0.000006820303,0.0001873022,0.000004059482,0.00007388109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002513215,"threshold_uncertainty_score":0.006598115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01317961236215255,"score_gpt":0.2317282690700341,"score_spread":0.2185486567078815,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}