{"id":"W4308248132","doi":"10.7759/cureus.31058","title":"An Open-Labeled Randomized Prospective Multi-center Study to Evaluate the Efficacy and Safety of Intra-articular Injection of OSSINEXT™, an Autologous Growth Factor Concentrate (AGFC) Compared to Hyaluronic Acid (HA) in Knee Osteoarthritis","year":2022,"lang":"en","type":"article","venue":"Cureus","topic":"Periodontal Regeneration and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Hyaluronic acid; Osteoarthritis; Visual analogue scale; Surgery; Platelet-rich plasma; Adverse effect; Internal medicine; Pathology; Platelet","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003830973,0.00170274,0.004990995,0.000608211,0.0009255551,0.00115827,0.001464829,0.002530646,0.007680427],"category_scores_gemma":[0.002478887,0.001139089,0.001775277,0.0005843132,0.002361654,0.001696256,0.0006587188,0.003327953,0.001383896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008596265,"about_ca_system_score_gemma":0.001988465,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006452248,"about_ca_topic_score_gemma":0.001106921,"domain_scores_codex":[0.9982349,0.0007510209,0.0001691455,0.0003628875,0.0002374064,0.0002447387],"domain_scores_gemma":[0.9966403,0.000841419,0.0007324048,0.0003101916,0.0003609325,0.001114678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9105387,0.08045731,0.001399569,0.0003737509,0.0004087379,0.00005340038,0.00008459483,0.0001241704,0.002382172,0.00007176294,0.0002113755,0.003894434],"study_design_scores_gemma":[0.424125,0.5711089,0.003392881,0.00002865101,0.0002589716,0.00003410702,0.00005703473,0.0001994772,0.0003817804,0.00006960479,0.0003254842,0.00001824762],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862705,0.001056892,0.000461887,0.0002330241,0.0004333663,0.01027731,0.0004605896,0.00003314978,0.000773289],"genre_scores_gemma":[0.9760191,0.00108499,0.002135768,0.001221612,0.0007995524,0.01498454,0.0007295854,0.00001352098,0.003011271],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007680427,"threshold_uncertainty_score":0.02569354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0290098740057254,"score_gpt":0.3318290329350054,"score_spread":0.30281915892928,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}