{"id":"W4308294023","doi":"10.1016/j.arcmed.2022.10.004","title":"Telomeres, Telomerase and Cancer","year":2022,"lang":"en","type":"review","venue":"Archives of Medical Research","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Terry Fox Research Institute; University of British Columbia","funders":"","keywords":"Telomere; Telomerase; Epigenome; Biology; Genome instability; DNA repair; DNA damage; Epigenetics; Premature aging; Genetics; Senescence; Cancer; Cell biology; Cancer research; DNA methylation; DNA; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00293006,0.0004926433,0.002695542,0.001585574,0.0003172176,0.00003257693,0.001154586,0.0004142837,0.009557957],"category_scores_gemma":[0.005122595,0.0003668688,0.0005267209,0.001300614,0.002331278,0.00005034714,0.00157233,0.004259622,0.00004033799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000113079,"about_ca_system_score_gemma":0.004751589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001252422,"about_ca_topic_score_gemma":0.00005450474,"domain_scores_codex":[0.9901413,0.001342728,0.00111917,0.001013689,0.005277544,0.001105609],"domain_scores_gemma":[0.9897695,0.007425364,0.0002325461,0.0009722427,0.00007944525,0.001520938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001014252,0.0002873234,0.00008769585,0.03223577,0.0002964187,0.0006808158,0.0003234932,1.660008e-8,0.000004429598,0.000498237,0.00292856,0.9625558],"study_design_scores_gemma":[0.0007174714,0.0003803884,0.000106147,0.01882206,0.0002738742,0.0003330821,0.0001820305,0.00002514766,0.000007182499,0.0001570193,0.9787019,0.0002936262],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001698068,0.9913889,0.000004948622,0.001309709,0.0001992581,0.001224681,0.0001408811,0.00004935497,0.005512503],"genre_scores_gemma":[0.00005828292,0.9954011,0.0001981792,0.0001356507,0.0004697948,0.0004804342,0.0001620033,0.000110157,0.002984411],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9757734,"threshold_uncertainty_score":0.9998783,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2332867100727672,"score_gpt":0.512001533443098,"score_spread":0.2787148233703308,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}