{"id":"W4308394414","doi":"10.1002/tcr.202200218","title":"Exploring Nucleobase Modifications in Oligonucleotide Analogues for Use as Environmentally Responsive Fluorophores and Beyond","year":2022,"lang":"en","type":"review","venue":"The Chemical Record","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"Context (archaeology); Nucleobase; Nucleic acid; Nanotechnology; Oligonucleotide; Scope (computer science); Computer science; Chemistry; Computational biology; Biology; DNA; Biochemistry; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002308066,0.0002967668,0.0005377002,0.00009095105,0.0001229377,0.00003437363,0.0002858943,0.0001527554,0.000005220506],"category_scores_gemma":[0.0004112519,0.0002198732,0.0002892634,0.0001559664,0.0001943294,0.000008275337,0.0003081957,0.0002548234,0.000002043229],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008129879,"about_ca_system_score_gemma":0.00004927946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002712758,"about_ca_topic_score_gemma":0.00001386677,"domain_scores_codex":[0.9985546,0.0001349057,0.0003950655,0.0005654302,0.0001085965,0.0002414102],"domain_scores_gemma":[0.9989018,0.0002840888,0.000194763,0.000533394,0.0000160441,0.00006987058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001329982,0.00007142731,0.000002874752,0.0002777145,0.0001286731,0.000005194817,0.00002785502,4.011411e-7,0.04863741,0.00004997688,0.0005170142,0.9501485],"study_design_scores_gemma":[0.0001031808,0.0001091366,0.000002260922,0.0002002971,0.0002468695,0.00001898543,0.00008187581,0.000008448404,0.02441702,0.0001751391,0.9743301,0.0003066541],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.09595951,0.9017215,0.00009611495,0.0001433721,0.00008588564,0.001366553,0.0004090733,0.00005113429,0.0001668179],"genre_scores_gemma":[0.002129527,0.9919677,0.004335558,0.0001259425,0.00009912844,0.0004320108,0.0007002382,0.00005288691,0.0001570498],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9738131,"threshold_uncertainty_score":0.8966167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1207704091223563,"score_gpt":0.329288956912318,"score_spread":0.2085185477899618,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}