{"id":"W4308430753","doi":"10.1016/j.heliyon.2022.e11432","title":"Short- and long-term administration of buprenorphine improved gene expression of P2X4 and GABAA receptors in the hippocampus of methamphetamine rats","year":2022,"lang":"en","type":"article","venue":"Heliyon","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"University of Tabriz; Hamadan University of Medical Sciences","keywords":"Meth-; GABAA receptor; Methamphetamine; Pharmacology; Receptor; Hippocampus; Hippocampal formation; Benzodiazepine; Chemistry; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007602342,0.0004720337,0.0003304935,0.0002625645,0.0001466153,0.0002304261,0.0002489395,0.0003767357,0.003044344],"category_scores_gemma":[0.00009605248,0.0001886393,0.0001874305,0.000116173,0.0003972286,0.0003620015,0.0001874396,0.001108942,0.0003068399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002568433,"about_ca_system_score_gemma":0.0002194649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006844508,"about_ca_topic_score_gemma":0.002055794,"domain_scores_codex":[0.9998848,0.00001266177,0.000007700054,0.00002961545,0.00002284141,0.000042226],"domain_scores_gemma":[0.9998692,0.000008541293,0.00003384974,0.0000145805,0.00001263309,0.00006110498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009802072,0.0001213314,0.0001950184,0.00002754396,0.00000744463,0.00004030375,0.00002161159,0.00002273011,0.9963828,0.00008053661,0.00004382865,0.002076599],"study_design_scores_gemma":[0.0001468866,0.003124862,0.02162013,0.00002196191,0.0000667542,0.0001763596,0.0002196756,0.0005396862,0.9722059,0.0001819121,0.001679923,0.00001593388],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976349,0.0006166179,0.0005226342,0.0001728285,0.00004489724,0.00001432453,0.0002952049,0.00004440923,0.000654149],"genre_scores_gemma":[0.98857,0.0007106125,0.0009019733,0.00009098988,0.00001794779,0.00007840842,0.0002941159,0.00002080083,0.009315116],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003044344,"threshold_uncertainty_score":0.01018435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01291984986795374,"score_gpt":0.2583566818483513,"score_spread":0.2454368319803975,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}