{"id":"W4308456919","doi":"10.3390/cells11213514","title":"The Potential for Placental Activation of PPARγ to Improve the Angiogenic Profile in Preeclampsia","year":2022,"lang":"en","type":"article","venue":"Cells","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; University of Toronto; Sunnybrook Health Science Centre","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Heart, Lung, and Blood Institute","keywords":"Placental growth factor; Preeclampsia; Placenta; Angiogenesis; Rosiglitazone; Trophoblast; Umbilical vein; Endocrinology; Endoglin; PPAR agonist; Peroxisome proliferator-activated receptor; Internal medicine; Vascular endothelial growth factor; Downregulation and upregulation; Biology; Receptor; Cell biology; Medicine; Fetus; Stem cell; Pregnancy; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003784923,0.0001930557,0.0003583306,0.0002219112,0.0001356556,0.0004480871,0.0002518563,0.0003027606,0.00144866],"category_scores_gemma":[0.0003980155,0.0001315974,0.0003002961,0.0002012922,0.0001901751,0.0002062765,0.0003168142,0.0007981521,0.0001980035],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000210005,"about_ca_system_score_gemma":0.0003512402,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003413315,"about_ca_topic_score_gemma":0.0005181219,"domain_scores_codex":[0.9998552,0.00005388117,0.00001469053,0.00001949486,0.00002509571,0.0000316117],"domain_scores_gemma":[0.999899,0.00002902649,0.0000194369,0.00001685589,0.00001755912,0.00001810166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002025265,0.0003226105,0.001726686,0.0007866576,0.00008610744,0.0006141102,0.0001545379,0.000371682,0.9414167,0.00140423,0.0006434568,0.05044805],"study_design_scores_gemma":[0.0007314183,0.008378954,0.04003424,0.0002641719,0.0006299614,0.003559276,0.0007329946,0.002201205,0.8565243,0.002953812,0.08394214,0.00004749019],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9299567,0.04040845,0.01697971,0.003791647,0.000530292,0.0001602481,0.0003644578,0.0002796112,0.007528824],"genre_scores_gemma":[0.9706447,0.02013504,0.004107946,0.000701695,0.0001193778,0.00009803278,0.0003106596,0.00003003408,0.003852549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00144866,"threshold_uncertainty_score":0.004846275,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01054912644329109,"score_gpt":0.2478895864271175,"score_spread":0.2373404599838264,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}