{"id":"W4308557162","doi":"10.1093/brain/awac301","title":"Genome-wide contribution of common short-tandem repeats to Parkinson’s disease genetic risk","year":2022,"lang":"en","type":"review","venue":"Brain","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Montreal Neurological Institute and Hospital","funders":"National Institute of Environmental Health Sciences; National Institute of Neurological Disorders and Stroke; National Institute on Aging; U.S. Department of Health and Human Services; National Institutes of Health; Michael J. Fox Foundation for Parkinson's Research; U.S. Department of Defense","keywords":"Genetics; Genome-wide association study; Biology; Single-nucleotide polymorphism; Genetic association; Genome; Disease; Indel; Gene; Medicine; Genotype; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001336033,0.0004939359,0.0007697934,0.001389337,0.0003742973,0.0009030573,0.000524218,0.0006581327,0.001618805],"category_scores_gemma":[0.003744906,0.0002954942,0.001645909,0.001888727,0.0004152764,0.0002537685,0.0006295705,0.0006751081,0.0001645517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002215982,"about_ca_system_score_gemma":0.0002442785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004934343,"about_ca_topic_score_gemma":0.004086463,"domain_scores_codex":[0.9982978,0.0004192651,0.0001435684,0.000764831,0.0002598897,0.0001147518],"domain_scores_gemma":[0.9979987,0.0008136886,0.0005250911,0.0002784975,0.0001873419,0.0001966247],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0006263754,0.00001968226,0.9846389,0.0000761163,0.004776203,0.0003971759,0.0001126501,0.0004541018,0.002947973,0.0001120904,0.0001990397,0.005639758],"study_design_scores_gemma":[0.00002871642,0.00006203362,0.9957165,0.00001873697,0.001892104,0.0005113622,0.00007144991,0.0007420237,0.0003436684,0.0002830786,0.0003196016,0.00001062407],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9933698,0.004294178,0.0008827149,0.0001598469,0.00002785308,0.000007332193,0.0007972405,0.00003195663,0.0004290888],"genre_scores_gemma":[0.9984743,0.000603763,0.0002638951,0.00003233882,0.00002184343,0.000005692832,0.000469369,0.000009156901,0.0001196349],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004934343,"threshold_uncertainty_score":0.009811223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02116276209300247,"score_gpt":0.299034366012478,"score_spread":0.2778716039194755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}