{"id":"W4308590528","doi":"10.1016/j.oraloncology.2022.106176","title":"O3.2 Loss of LRP1B expression drives chemo and radiation resistance in HPV-positive head and neck cancer","year":2022,"lang":"en","type":"article","venue":"Oral Oncology","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Head and neck cancer; Medicine; Head and neck; Cancer; Oncology; Internal medicine; Radiation therapy; Cancer research; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009489575,0.00006856361,0.0001406245,0.00003098037,0.00006042053,0.000003421952,0.00005094827,0.00007356063,0.00004094631],"category_scores_gemma":[0.00001631206,0.00006759183,0.00001745206,0.00005677121,0.00008390942,0.000004101172,0.0001248524,0.00007723,1.420718e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003571468,"about_ca_system_score_gemma":0.0000682566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001332607,"about_ca_topic_score_gemma":0.0006924168,"domain_scores_codex":[0.9994226,0.00008616791,0.0001218911,0.0002058765,0.00004942812,0.0001140777],"domain_scores_gemma":[0.9997775,0.00001085554,0.00008061391,0.00008010119,0.00002017992,0.00003073515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008068393,0.000149792,0.05760422,0.00003106752,0.00001759121,0.00001870199,0.0005557364,0.00003592317,0.9125808,0.0002386216,0.00113088,0.02682985],"study_design_scores_gemma":[0.003509486,0.002458182,0.327381,0.00004485309,0.00001657397,0.00001931807,0.0005029058,0.00005793471,0.5477374,0.0005418957,0.1174458,0.0002846828],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939246,0.004700691,0.00002108797,0.000459302,0.00005960634,0.0001309716,0.00003636979,0.000002515495,0.0006648314],"genre_scores_gemma":[0.9980512,0.0007077805,0.0005582444,0.0002013934,0.00004803263,0.00006163522,0.00003323252,0.000007194802,0.0003312901],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3648434,"threshold_uncertainty_score":0.2756315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008780758192455117,"score_gpt":0.2920817284551015,"score_spread":0.2833009702626464,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}