{"id":"W4308592508","doi":"10.3389/fimmu.2022.1043375","title":"A single birth dose of Hepatitis B vaccine induces polyfunctional CD4+ T helper cells","year":2022,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Allergy and Infectious Diseases; Medical Research Council; National Institutes of Health; UK Research and Innovation","keywords":"Immunology; Virology; Vaccination; Hepatitis B vaccine; Medicine; Hepatitis B; Hepatitis B virus; HBsAg; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002975307,0.0003051208,0.0003086443,0.0002524988,0.00009789587,0.0001962768,0.0001257388,0.0003032699,0.001821751],"category_scores_gemma":[0.0004105056,0.0001724202,0.000158358,0.00008959173,0.0001807237,0.0001462503,0.0002498004,0.0006412077,0.0004380356],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001120238,"about_ca_system_score_gemma":0.0001604511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001361974,"about_ca_topic_score_gemma":0.0002014147,"domain_scores_codex":[0.9998272,0.00004757367,0.00001308395,0.00004137074,0.00002695436,0.00004387083],"domain_scores_gemma":[0.9997111,0.0001088507,0.00004708454,0.00003830944,0.000027407,0.00006729007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004909835,0.0002124412,0.001743428,0.00009209977,0.000004454633,0.0001013917,0.00007976106,0.00004615019,0.9902335,0.00004837882,0.00005939244,0.00688793],"study_design_scores_gemma":[0.0001749183,0.01501759,0.05444344,0.00004904192,0.00004615052,0.001443244,0.0002209663,0.001099178,0.9240617,0.0001909716,0.003238533,0.00001427062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980518,0.0003662937,0.0007235394,0.0000320479,0.00002164593,0.00003469185,0.00006315274,0.00004706645,0.0006598442],"genre_scores_gemma":[0.996225,0.000323213,0.001426866,0.00004984647,0.00002681392,0.00005276136,0.0001753589,0.00001388931,0.001706205],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001821751,"threshold_uncertainty_score":0.006094396,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01328515305674919,"score_gpt":0.2288550980867576,"score_spread":0.2155699450300084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}