{"id":"W4308721983","doi":"10.3390/cancers14215453","title":"CAXII Is a Surrogate Marker for Luminal Breast Tumors Regulated by ER and GATA3","year":2022,"lang":"en","type":"article","venue":"Cancers","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of British Columbia; Institute for Research in Immunology and Cancer","funders":"Canadian Institutes of Health Research","keywords":"GATA3; FOXA1; Estrogen receptor; Estrogen receptor alpha; Cancer research; Estrogen; Breast cancer; Progesterone receptor; Internal medicine; Medicine; Cancer; Endocrinology; Biology; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00035739,0.0002484472,0.000287873,0.0007156926,0.0002217413,0.0004858958,0.0002041989,0.0002880278,0.001812384],"category_scores_gemma":[0.0004906579,0.0001631138,0.0001702851,0.0008739496,0.0002725197,0.0001641746,0.0002609402,0.0004288504,0.0003372011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004092862,"about_ca_system_score_gemma":0.0002110226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001222217,"about_ca_topic_score_gemma":0.002656659,"domain_scores_codex":[0.9997198,0.00003477841,0.0000179118,0.0000885738,0.0000876229,0.00005136672],"domain_scores_gemma":[0.9996237,0.00008064744,0.0001446106,0.00004042558,0.00005543114,0.00005513426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009609375,0.0000409628,0.2087934,0.0002079677,0.00009877933,0.000168751,0.00009983015,0.000324365,0.7756638,0.0003015674,0.0008617162,0.01247792],"study_design_scores_gemma":[0.00002594542,0.0002128325,0.8158896,0.00002429723,0.0001038755,0.001739062,0.0001258575,0.002656235,0.171453,0.0004049141,0.007347895,0.00001643555],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982442,0.003082988,0.005666695,0.0001213346,0.00003009055,0.00006057498,0.0048877,0.0002587345,0.003449904],"genre_scores_gemma":[0.988676,0.0006190673,0.004769536,0.00008013522,0.00001203348,0.00006695624,0.004248652,0.00004212782,0.001485478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001812384,"threshold_uncertainty_score":0.006062984,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003541756786333807,"score_gpt":0.2146554759494755,"score_spread":0.2111137191631416,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}