{"id":"W4308771760","doi":"10.1007/978-3-031-11454-0_9","title":"Pathways of DNA Demethylation","year":2022,"lang":"en","type":"article","venue":"Advances in experimental medicine and biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Calgary","funders":"","keywords":"Reprogramming; Biology; DNA demethylation; DNA methylation; Epigenetics; Epigenome; Chromatin; Induced pluripotent stem cell; Cell biology; Context (archaeology); Genetics; Embryonic stem cell; DNA; Cell; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004131164,0.0006198088,0.0003236589,0.00116526,0.0006580499,0.001431457,0.000541632,0.0006099659,0.006816994],"category_scores_gemma":[0.000450973,0.0003018979,0.0004010979,0.0005717311,0.0006095896,0.001304413,0.001154069,0.001096139,0.002117361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009251098,"about_ca_system_score_gemma":0.000915033,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006987799,"about_ca_topic_score_gemma":0.0006290876,"domain_scores_codex":[0.9997432,0.00004719705,0.00001510576,0.0000766849,0.00006913232,0.00004874064],"domain_scores_gemma":[0.9997258,0.00004776385,0.00004192334,0.00004356292,0.00008254555,0.00005833222],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005288775,0.0001051087,0.002406156,0.001162492,0.0001080767,0.0007540595,0.0004568717,0.001597228,0.6266425,0.2423995,0.003914969,0.1199243],"study_design_scores_gemma":[0.00004114267,0.0003819071,0.008599157,0.0001899586,0.00005553775,0.00120105,0.0004601965,0.00291379,0.7190192,0.07592632,0.1911556,0.00005611771],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"methods","genre_gemma":"review","genre_scores_codex":[0.2966539,0.1536464,0.3091405,0.0108131,0.00205625,0.001043077,0.005648945,0.002307857,0.21869],"genre_scores_gemma":[0.8126279,0.05712347,0.03852247,0.0009981684,0.0003168288,0.0004767568,0.002952146,0.00009970946,0.08688248],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.006816994,"threshold_uncertainty_score":0.02280509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02717430727329104,"score_gpt":0.3378052794061748,"score_spread":0.3106309721328838,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}