{"id":"W4308834504","doi":"10.1002/art.42391","title":"Deucravacitinib, a Tyrosine Kinase 2 Inhibitor, in Systemic Lupus Erythematosus: A Phase <scp>II</scp>, Randomized, <scp>Double‐Blind</scp>, <scp>Placebo‐Controlled</scp> Trial","year":2022,"lang":"en","type":"article","venue":"Arthritis & Rheumatology","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":248,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Bristol-Myers Squibb Canada; Bristol-Myers Squibb","keywords":"Double blind; Placebo; Medicine; Pharmacology; Pathology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00184761,0.0008731185,0.001692805,0.0002234093,0.0002390554,0.0006456883,0.0004400084,0.0009656022,0.002443598],"category_scores_gemma":[0.0009089049,0.0002957179,0.001038441,0.0002390469,0.0004840041,0.0005220859,0.0001626478,0.001223657,0.0003564213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004866307,"about_ca_system_score_gemma":0.000809197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004671539,"about_ca_topic_score_gemma":0.001359837,"domain_scores_codex":[0.9995847,0.0002283746,0.00003633073,0.00006561491,0.00004029292,0.00004460764],"domain_scores_gemma":[0.9993804,0.0001926723,0.0001781984,0.00003187553,0.00004491056,0.000171916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8917049,0.005612825,0.003440265,0.002450991,0.002046779,0.0001144074,0.00009692868,0.001326103,0.01154161,0.0001704453,0.002764981,0.0787299],"study_design_scores_gemma":[0.9159307,0.07344104,0.005766926,0.00007774951,0.0006987523,0.0002090287,0.00001938647,0.0007807742,0.001498844,0.00009471517,0.001468414,0.00001368346],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982942,0.01212603,0.0005272024,0.0005411975,0.0002147221,0.001443525,0.0007304648,0.00009651092,0.001378505],"genre_scores_gemma":[0.9906977,0.004569202,0.0008096559,0.0005384508,0.0002265995,0.001056929,0.0008552797,0.00001048088,0.001235587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002443598,"threshold_uncertainty_score":0.009771228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02133392397920848,"score_gpt":0.2942335212175657,"score_spread":0.2728995972383573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}