{"id":"W4308907426","doi":"10.1016/j.anai.2022.08.627","title":"LONG-TERM SAFETY AND EFFICACY OF DUPILUMAB IN CHILDREN WITH ASTHMA: LIBERTY ASTHMA EXCURSION","year":2022,"lang":"en","type":"article","venue":"Annals of Allergy Asthma & Immunology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Quebec - Clinical Research Organization in Cancer","funders":"","keywords":"Dupilumab; Medicine; Asthma; Placebo; Eosinophil; Internal medicine; Adverse effect; Gastroenterology; Immunology; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002360926,0.0003302635,0.001293751,0.0003082708,0.0004116629,0.001085525,0.0004080892,0.0008788544,0.001632376],"category_scores_gemma":[0.003126352,0.0001755881,0.001398104,0.0002960232,0.0005703752,0.0008847113,0.0004076318,0.001855441,0.0003382452],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001517418,"about_ca_system_score_gemma":0.0007803392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001087466,"about_ca_topic_score_gemma":0.001960614,"domain_scores_codex":[0.9988633,0.0002420283,0.0001028042,0.0001759471,0.0003527925,0.0002631624],"domain_scores_gemma":[0.9973294,0.0008065176,0.0008751077,0.0001851827,0.0002579885,0.0005457775],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1163812,0.002057501,0.3767934,0.001563126,0.002709705,0.001712115,0.0006345407,0.0009916709,0.01600516,0.0008283472,0.006612381,0.4737108],"study_design_scores_gemma":[0.02081895,0.08878673,0.8502582,0.0006988195,0.004180653,0.005458293,0.0005384905,0.002142072,0.01072705,0.0004137807,0.01583603,0.0001407626],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9783865,0.01758093,0.0001951727,0.000990903,0.0001335234,0.00005795642,0.0007536326,0.00004008307,0.001861276],"genre_scores_gemma":[0.9968687,0.001313405,0.0002335898,0.0004053451,0.0001073137,0.00003481877,0.0004792833,0.000007423957,0.0005500846],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002360926,"threshold_uncertainty_score":0.01248592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01223386880048675,"score_gpt":0.2654013395485615,"score_spread":0.2531674707480747,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}