{"id":"W4309004602","doi":"10.3390/biom12111684","title":"Culture of Cancer Cells at Physiological Oxygen Levels Affects Gene Expression in a Cell-Type Specific Manner","year":2022,"lang":"en","type":"article","venue":"Biomolecules","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene expression; Cancer; Cancer cell; Cell biology; Cell; Gene; Biology; Cell type; Expression (computer science); Cell culture; Cancer research; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009007862,0.0001848046,0.0002243328,0.00005384288,0.00009345231,0.000007187908,0.0002518249,0.0001271612,0.0002631361],"category_scores_gemma":[0.000006407505,0.0001580531,0.0001182578,0.0001864461,0.00008946423,0.00000263634,0.0004144728,0.0001023237,0.000007614045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004134013,"about_ca_system_score_gemma":0.00005734794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004136225,"about_ca_topic_score_gemma":0.00002765781,"domain_scores_codex":[0.9987828,0.0001282926,0.0001779557,0.0004485146,0.0001886499,0.0002738517],"domain_scores_gemma":[0.9994659,0.000004791436,0.0001119066,0.0003091615,0.00003985381,0.00006842986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002047571,0.000130369,0.0001048223,0.00002329403,0.0000137839,0.000005872809,0.0001482876,0.0002855877,0.965123,0.000007309519,0.03355025,0.0004026439],"study_design_scores_gemma":[0.000578394,0.0001705121,0.002572087,0.000007944313,0.000008693638,0.000003566373,0.00009885262,0.000004853667,0.8143101,0.000010755,0.1820581,0.0001761292],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9658126,0.03248905,0.00004195997,0.00003024373,0.0008816361,0.0002294788,0.0001913701,0.000009441512,0.0003141793],"genre_scores_gemma":[0.9932232,0.00348405,0.0006604017,0.0001747603,0.0005114987,0.00007523661,0.0001531193,0.00002577622,0.001691996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1508129,"threshold_uncertainty_score":0.6445217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01794029964836295,"score_gpt":0.259330693161802,"score_spread":0.2413903935134391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}