{"id":"W4309004602","doi":"10.3390/biom12111684","title":"Culture of Cancer Cells at Physiological Oxygen Levels Affects Gene Expression in a Cell-Type Specific Manner","year":2022,"lang":"en","type":"article","venue":"Biomolecules","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Brock University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Gene expression; Cancer; Cancer cell; Cell biology; Cell; Gene; Biology; Cell type; Expression (computer science); Cell culture; Cancer research; Genetics; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000197924,0.0002380203,0.0003769213,0.0003022481,0.0004352703,0.0005093946,0.0001861885,0.0002544389,0.002057021],"category_scores_gemma":[0.0002150267,0.0001861244,0.0004192962,0.0007421418,0.000278062,0.0001922447,0.0002931097,0.0007475986,0.000816197],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002545983,"about_ca_system_score_gemma":0.0003677485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001863753,"about_ca_topic_score_gemma":0.004431271,"domain_scores_codex":[0.9995673,0.00003256401,0.00004118428,0.0001388736,0.000135324,0.00008460569],"domain_scores_gemma":[0.9998747,0.00003424541,0.00001965047,0.00002389459,0.00003454742,0.00001284954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008931367,0.00004467304,0.001360647,0.0001074098,0.00002207355,0.00005057111,0.00006803983,0.000159769,0.9948955,0.00008424448,0.0005416985,0.002575996],"study_design_scores_gemma":[0.00002403542,0.00038715,0.04011872,0.00003196077,0.00008442397,0.0003097217,0.0001892726,0.002207974,0.9306392,0.0001810035,0.02579902,0.00002747327],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9508212,0.004597782,0.0228938,0.0005948715,0.0003188159,0.0003241823,0.01282156,0.0005780812,0.007049748],"genre_scores_gemma":[0.9282454,0.006495826,0.0285531,0.001161268,0.00008025497,0.001476397,0.02256284,0.0002739674,0.01115087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002057021,"threshold_uncertainty_score":0.006881416,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01794029964836295,"score_gpt":0.259330693161802,"score_spread":0.2413903935134391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}