{"id":"W4309014062","doi":"10.1007/978-1-0716-2740-2_15","title":"Induction of Human T Cell Development In Vitro with OP9-DL4-7FS Cells Expressing Human Cytokines","year":2022,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Sunnybrook Hospital","funders":"Canadian Institutes of Health Research","keywords":"Cell biology; Biology; Haematopoiesis; Stromal cell; Stem cell; Cancer research","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007386161,0.001023557,0.0005500884,0.0006728788,0.0002832937,0.0006818752,0.0004275732,0.0005318517,0.005170318],"category_scores_gemma":[0.000303792,0.0002838068,0.0006881419,0.0003666733,0.0003315994,0.0003175451,0.0004438905,0.002184051,0.002487367],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003564573,"about_ca_system_score_gemma":0.0003385123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008917974,"about_ca_topic_score_gemma":0.0008845039,"domain_scores_codex":[0.9992411,0.0001535072,0.00009305728,0.0001228268,0.0001739726,0.0002156735],"domain_scores_gemma":[0.9994862,0.000226023,0.00005490857,0.00009921809,0.0000561862,0.00007737599],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003578696,0.00008215872,0.0001727149,0.00006973704,0.000008512555,0.0001014743,0.00008072021,0.0001476464,0.9960377,0.0004997985,0.0002431892,0.002198289],"study_design_scores_gemma":[0.00002297847,0.0001352194,0.0003792335,0.000005517068,0.000009483076,0.00006326752,0.00001184488,0.000437924,0.9943836,0.00003695874,0.004511843,0.000002074891],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.8989666,0.004334527,0.05544476,0.0003658712,0.0006401172,0.00132464,0.005979514,0.001427155,0.03151682],"genre_scores_gemma":[0.9553356,0.00161529,0.01954728,0.0001595534,0.0001283243,0.0005517725,0.005406896,0.0002413888,0.01701381],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.005170318,"threshold_uncertainty_score":0.01729643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05628862039573744,"score_gpt":0.4259406382711483,"score_spread":0.3696520178754108,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}