{"id":"W4309016122","doi":"10.1093/neuonc/noac209.128","title":"STEM-11. POLYAMINE METABOLISM AND INFLAMMATORY STATE CONTROL A VIRAL MIMICRY-DRIVEN QUIESCENT PHENOTYPE IN GLIOMA STEM CELLS (GSCS)","year":2022,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Biology; Epigenetics; Stem cell; Cell biology; Downregulation and upregulation; Polycomb-group proteins; Cancer research; Genetics; Gene expression; Gene; Repressor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001038771,0.0002404403,0.0002843683,0.0003479545,0.0001089514,0.0003000231,0.0001245056,0.0002091521,0.001358962],"category_scores_gemma":[0.0001221754,0.00009543794,0.0002318824,0.0002492542,0.0001813285,0.000113638,0.0001773703,0.000280031,0.0003573722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000236223,"about_ca_system_score_gemma":0.0001325183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007668019,"about_ca_topic_score_gemma":0.001041687,"domain_scores_codex":[0.9998761,0.00001968332,0.00001761734,0.00002491163,0.00003722205,0.00002443334],"domain_scores_gemma":[0.9998773,0.00001615246,0.00003208987,0.0000196106,0.0000180598,0.00003673928],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002526858,0.0000371017,0.00280405,0.00003963413,0.000009675771,0.00009487725,0.00004888914,0.00007406919,0.9939601,0.00006093875,0.00005650756,0.002561253],"study_design_scores_gemma":[0.00002494882,0.001508969,0.09057845,0.00001027648,0.00003978618,0.0007628754,0.0001924594,0.001307397,0.9019943,0.00009205847,0.003479906,0.000008509426],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971132,0.0006833006,0.0006127901,0.00002947961,0.000008834281,0.00003677912,0.0008377737,0.00005124867,0.000626658],"genre_scores_gemma":[0.9967971,0.0002099852,0.0003896093,0.00003778568,0.000004109762,0.00003804828,0.001225049,0.000008664266,0.001289627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001358962,"threshold_uncertainty_score":0.004546165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01102132014708392,"score_gpt":0.2621546522714016,"score_spread":0.2511333321243177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}