{"id":"W4309029787","doi":"10.1016/j.ijrobp.2022.09.009","title":"LUSTRE: A Phase III Randomized Trial of Stereotactic Body Radiotherapy (SBRT) vs. Conventionally Hypofractionated Radiotherapy (CRT) for Medically Inoperable Stage I Non-Small Cell Lung Cancer (NSCLC)","year":2022,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Lung Cancer Diagnosis and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Thunder Bay Regional Health Sciences Centre; University of Calgary; Centre Hospitalier de l’Université de Montréal; Health Sciences Centre; CancerCare Manitoba; Windsor Regional Hospital; Université de Montréal; Hôpital Maisonneuve-Rosemont; Sunnybrook Health Science Centre; Juravinski Cancer Centre; McGill University Health Centre; McMaster University","funders":"","keywords":"Medicine; Randomized controlled trial; Radiosurgery; Lung cancer; Hazard ratio; Radiation therapy; Clinical endpoint; Stage (stratigraphy); Dose fractionation; Pneumonitis; Radiology; Nuclear medicine; Oncology; Internal medicine; Lung; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001394641,0.002305609,0.002464171,0.0004050087,0.0003804311,0.0009687283,0.001544078,0.00155674,0.01073211],"category_scores_gemma":[0.001556668,0.0005665527,0.00236025,0.0003501743,0.001283932,0.001413425,0.0006308859,0.004338413,0.001750746],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007494607,"about_ca_system_score_gemma":0.0008276145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001310189,"about_ca_topic_score_gemma":0.003004473,"domain_scores_codex":[0.9995135,0.0002474272,0.00002363345,0.0001081431,0.00003920374,0.00006816608],"domain_scores_gemma":[0.9994346,0.0001713439,0.0001179989,0.0000569774,0.00002472415,0.0001942972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9803197,0.005228627,0.0003133671,0.0003125555,0.0007356482,0.00002123922,0.00003922293,0.0005663272,0.003521799,0.0001487651,0.0008477144,0.007944967],"study_design_scores_gemma":[0.9408951,0.05614894,0.0009691549,0.00001846572,0.0003806239,0.00002248053,0.00002246778,0.0006300015,0.0003524996,0.0001616921,0.0003825599,0.00001598191],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984675,0.002412562,0.001003201,0.001392231,0.00108178,0.002885374,0.002104206,0.0004380652,0.004007415],"genre_scores_gemma":[0.971492,0.001857381,0.003397704,0.002859247,0.0007220171,0.005316715,0.003593749,0.0001224416,0.01063872],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01073211,"threshold_uncertainty_score":0.0359025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01607355022878398,"score_gpt":0.3597189400945072,"score_spread":0.3436453898657232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}