{"id":"W4309070457","doi":"10.1371/journal.ppat.1010968","title":"Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects","year":2022,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Hepatitis C virus research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"Office of Research Infrastructure Programs, National Institutes of Health; National Center for Research Resources; Canada Excellence Research Chairs, Government of Canada; NIHR Oxford Biomedical Research Centre; Fonds de Recherche du Québec - Santé; National Institute of Allergy and Infectious Diseases; Medical Research Council; Institute of Infection and Immunity; Public Health Agency; Canadian Institutes of Health Research; National Institute for Health and Care Research; National Institutes of Health; Public Health Agency of Canada; Emory University; Styrelsen för Internationellt Utvecklingssamarbete","keywords":"Immunology; Virology; Immune system; Hepatitis C virus; Antibody; Transcriptome; Vaccination; Medicine; Biology; Virus; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001471455,0.0001395035,0.0002246236,0.0003165205,0.0001652048,0.0002914695,0.00007215113,0.0002274637,0.0008729034],"category_scores_gemma":[0.000394922,0.00009285363,0.0001042561,0.00022223,0.0001919204,0.0001079876,0.0001685716,0.0002101654,0.0001435073],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009735992,"about_ca_system_score_gemma":0.00008016564,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006317947,"about_ca_topic_score_gemma":0.0008795312,"domain_scores_codex":[0.9998653,0.00002420885,0.000008808438,0.00005256366,0.00001491784,0.00003416285],"domain_scores_gemma":[0.9998565,0.00004362982,0.00003462985,0.00001299197,0.00002248998,0.0000296505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.003415063,0.0001685798,0.4440961,0.00008769293,0.00008548785,0.0005476947,0.0009984336,0.0002290083,0.5357823,0.0001289368,0.0002408483,0.01421987],"study_design_scores_gemma":[0.00002161482,0.001062569,0.9860758,0.000007263156,0.00004143194,0.0006775256,0.0004942779,0.0006188215,0.01036694,0.00007972266,0.0005446575,0.000009317577],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993445,0.00006770342,0.0001336393,0.00001191374,0.000002682814,0.000008222353,0.0002741837,0.000003890527,0.0001532204],"genre_scores_gemma":[0.9987773,0.00004438116,0.0002384374,0.00004000875,0.000005401568,0.00002013348,0.0005181484,0.00000349231,0.0003527788],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008729034,"threshold_uncertainty_score":0.002920151,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03372478540222246,"score_gpt":0.2736471926914631,"score_spread":0.2399224072892407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}