{"id":"W4309094833","doi":"10.1111/imr.13169","title":"Alternative pathway activation in pregnancy, a measured amount “complements” a successful pregnancy, too much results in adverse events","year":2022,"lang":"en","type":"review","venue":"Immunological Reviews","topic":"Pregnancy and preeclampsia studies","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Medical Research Council; Medical Research Council Canada","keywords":"Pregnancy; Complement system; Innate immune system; Immune system; Biology; Acquired immune system; Alternative complement pathway; Immunology; Adaptation (eye); Complement (music); Fetus; Classical complement pathway; Immunity; Neuroscience; Phenotype; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004271313,0.0004911918,0.0008713491,0.001577908,0.0002650397,0.0009117024,0.00044853,0.0007250569,0.003671919],"category_scores_gemma":[0.000773085,0.0001213594,0.0004102859,0.001628684,0.0004799057,0.0007790743,0.0004669747,0.001056097,0.001060938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004642617,"about_ca_system_score_gemma":0.001135201,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001015467,"about_ca_topic_score_gemma":0.001727778,"domain_scores_codex":[0.9997329,0.00005847383,0.0000520671,0.0000348697,0.00009941177,0.00002223005],"domain_scores_gemma":[0.9996991,0.0001586552,0.00005050241,0.000009264251,0.00006635923,0.00001606114],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000831557,0.00003821026,0.0003655067,0.02344064,0.0001108751,0.0003588678,0.0001202749,0.0001564615,0.003259037,0.004897286,0.02083212,0.9463375],"study_design_scores_gemma":[0.0000130894,0.00009130518,0.001623273,0.006620408,0.0001583231,0.003332826,0.000125966,0.00004933645,0.001207467,0.002320602,0.9844381,0.00001927435],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002323146,0.9974099,0.0001410804,0.0003526089,0.0003190338,0.000005221619,0.00002345228,0.00000552148,0.001510878],"genre_scores_gemma":[0.001376071,0.9975411,0.0001619042,0.0001498275,0.0001486302,0.000006332183,0.00002939163,0.000001168539,0.000585679],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003671919,"threshold_uncertainty_score":0.0122838,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1936488057676541,"score_gpt":0.3892421550712368,"score_spread":0.1955933493035828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}