{"id":"W4309098190","doi":"10.1182/bloodadvances.2022008204","title":"CNL and aCML should be considered as a single entity based on molecular profiles and outcomes","year":2023,"lang":"en","type":"article","venue":"Blood Advances","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Astellas Pharma; Academy of Medical Sciences; Cancer Research UK; Galecto; Sierra Oncology; CTI Biopharma; Incyte; Wellcome Trust; Celgene; Gilead Sciences; National Institute for Health and Care Research; Jazz Pharmaceuticals; European Hematology Association; Bristol-Myers Squibb","keywords":"Medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001945336,0.0001681162,0.0003143366,0.0001796752,0.00009484646,0.00004221339,0.00006830142,0.00007738958,0.00005297732],"category_scores_gemma":[0.001001438,0.0001320322,0.0000461376,0.0002508692,0.0002152346,0.0001050223,0.00009330536,0.0002024709,0.00002450548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002784319,"about_ca_system_score_gemma":0.0001294196,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003630231,"about_ca_topic_score_gemma":0.00001713039,"domain_scores_codex":[0.9986928,0.00005569623,0.0001600393,0.0003731487,0.000406708,0.0003115746],"domain_scores_gemma":[0.9990863,0.0003608352,0.00004468617,0.00027074,0.00006365492,0.0001737845],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008941754,0.001156395,0.6055536,0.001576445,0.0005671488,0.004374525,0.0006333775,0.00007544317,0.349221,0.002360443,0.004558726,0.02902872],"study_design_scores_gemma":[0.02051198,0.003905404,0.1824683,0.0006779034,0.0006506221,0.0002807712,0.001770432,0.002617127,0.7299381,0.004407091,0.05177342,0.0009988341],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845986,0.001201529,0.00001882347,0.0110006,0.00004761827,0.0005321272,0.00002963938,0.0001636109,0.002407497],"genre_scores_gemma":[0.9940061,0.0002842964,0.002043434,0.002487785,0.00003758214,0.00005648184,0.00003374321,0.0000304682,0.001020117],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4230853,"threshold_uncertainty_score":0.5384115,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04180531790906877,"score_gpt":0.3431559181950238,"score_spread":0.301350600285955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}