{"id":"W4309108410","doi":"10.1158/1538-7445.panca22-a077","title":"Abstract A077: PancreaCult™ Organoid Medium Kits support the robust establishment and expansion of human pancreatic duct organoids","year":2022,"lang":"en","type":"article","venue":"Cancer Research","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute; Canada's Michael Smith Genome Sciences Centre; Stemcell Technologies","funders":"","keywords":"Organoid; Matrigel; Pancreatic duct; Cell biology; PDX1; Cell culture; Biology; Chemistry; Pancreas; Endocrinology; Islet","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001383096,0.0008204323,0.0006777792,0.001038325,0.0004828472,0.001153725,0.0007415211,0.0007119101,0.007398968],"category_scores_gemma":[0.0008560916,0.0004076526,0.0008165641,0.0006765372,0.0003921416,0.0004957632,0.001013545,0.001410618,0.006640478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003083075,"about_ca_system_score_gemma":0.0007467922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006850394,"about_ca_topic_score_gemma":0.001212379,"domain_scores_codex":[0.9988626,0.0001877184,0.0001722173,0.0001780994,0.0004786896,0.0001206763],"domain_scores_gemma":[0.9989497,0.0002939976,0.0001295899,0.000203999,0.0002576186,0.0001651569],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002631598,0.0001351643,0.0006652689,0.0003748751,0.00001746046,0.0003158261,0.0001517211,0.0002875142,0.9787264,0.0004549547,0.003131598,0.01547605],"study_design_scores_gemma":[0.00006696652,0.0005167677,0.004456002,0.0001548465,0.00008506488,0.001160382,0.00006743069,0.001213661,0.9205607,0.0001794903,0.07149964,0.00003912117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5448636,0.01662778,0.3227955,0.001307215,0.001749803,0.00514144,0.03449033,0.009891944,0.06313235],"genre_scores_gemma":[0.6453224,0.00863307,0.2404263,0.0007812813,0.0002694472,0.006058641,0.04900391,0.001372298,0.04813266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007398968,"threshold_uncertainty_score":0.02475202,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07669552159149606,"score_gpt":0.3645652974582125,"score_spread":0.2878697758667165,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}