{"id":"W4309182708","doi":"10.1681/asn.2022050623","title":"Treatment Effect of the SGLT2 Inhibitor Empagliflozin on Chronic Syndrome of Inappropriate Antidiuresis: Results of a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial","year":2022,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Electrolyte and hormonal disorders","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universitätsspital Basel","keywords":"Empagliflozin; Medicine; Placebo; Free water clearance; Hyponatremia; Internal medicine; Crossover study; Randomized controlled trial; Endocrinology; Urology; Renal function; Diabetes mellitus; Type 2 diabetes","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002335525,0.000276858,0.003303305,0.0001283217,0.0001275799,0.000003950142,0.0004660337,0.00009330489,0.0000256419],"category_scores_gemma":[0.0002412348,0.0001341022,0.003603659,0.0005360371,0.001381095,0.00003768613,0.0001428135,0.0006042167,3.759437e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002672611,"about_ca_system_score_gemma":0.0007214276,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003069908,"about_ca_topic_score_gemma":0.00001059216,"domain_scores_codex":[0.99554,0.001425882,0.001643727,0.0002005854,0.0008782391,0.0003116307],"domain_scores_gemma":[0.9926791,0.001514462,0.00505479,0.0004896309,0.0001985472,0.00006343041],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8834444,0.000833419,0.00008017082,0.00008456378,0.004321035,0.000006352982,0.0007647261,0.0005728061,0.1071068,0.00001506868,0.002331563,0.0004390856],"study_design_scores_gemma":[0.9242047,0.05541819,0.001444521,0.00009396895,0.002668787,0.0002117759,0.0003581376,0.0001313422,0.01487922,0.00005989445,0.0004378973,0.00009154936],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9910915,0.001287256,0.000004220037,0.004694757,0.0001436371,0.002571426,0.00003607919,0.000003996949,0.0001670903],"genre_scores_gemma":[0.9982006,0.0007897964,0.0000462231,0.000480335,0.0001883707,0.00008154837,0.000002258871,0.00002465504,0.0001862359],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09222756,"threshold_uncertainty_score":0.5468531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337805812035252,"score_gpt":0.2860394963868423,"score_spread":0.2726614382664898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}