{"id":"W4309182708","doi":"10.1681/asn.2022050623","title":"Treatment Effect of the SGLT2 Inhibitor Empagliflozin on Chronic Syndrome of Inappropriate Antidiuresis: Results of a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial","year":2022,"lang":"en","type":"article","venue":"Journal of the American Society of Nephrology","topic":"Electrolyte and hormonal disorders","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Universitätsspital Basel","keywords":"Empagliflozin; Medicine; Placebo; Free water clearance; Hyponatremia; Internal medicine; Crossover study; Randomized controlled trial; Endocrinology; Urology; Renal function; Diabetes mellitus; Type 2 diabetes","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004036774,0.001822062,0.005999038,0.0005419122,0.000561857,0.001299871,0.0008893315,0.003306119,0.00581195],"category_scores_gemma":[0.004564628,0.0007453947,0.004017013,0.0004654845,0.00132017,0.001687766,0.0004504244,0.002540852,0.0006972951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007022463,"about_ca_system_score_gemma":0.001080463,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008458279,"about_ca_topic_score_gemma":0.001074216,"domain_scores_codex":[0.9980561,0.001074229,0.0002171737,0.0003216471,0.0001374459,0.0001935094],"domain_scores_gemma":[0.9975325,0.0009669231,0.0005581477,0.0002191602,0.0002583196,0.0004649814],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9896521,0.002355742,0.0001866025,0.0006815644,0.001462523,0.00001477844,0.00001798147,0.00008666607,0.0008523241,0.00002802404,0.000211227,0.00445033],"study_design_scores_gemma":[0.9751073,0.02269561,0.0006789136,0.00003138408,0.001011642,0.000008508746,0.000006608959,0.0001500394,0.0001167415,0.00004248008,0.0001423468,0.000008437362],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9676559,0.0167649,0.001627709,0.001314355,0.001955741,0.006721976,0.001633877,0.0002009401,0.002124585],"genre_scores_gemma":[0.9786001,0.005285498,0.002886015,0.00139327,0.001149529,0.007518719,0.001003704,0.00003561215,0.002127549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005999038,"threshold_uncertainty_score":0.02134871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01337805812035252,"score_gpt":0.2860394963868423,"score_spread":0.2726614382664898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}