{"id":"W4309243908","doi":"10.1128/spectrum.03183-22","title":"<i>Candida albicans</i> Reactive Oxygen Species (ROS)-Dependent Lethality and ROS-Independent Hyphal and Biofilm Inhibition by Eugenol and Citral","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Reactive oxygen species; Biofilm; Candida albicans; Microbiology; Eugenol; Chemistry; Lethality; Biology; Biochemistry; Toxicology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001150968,0.0003506928,0.0001733184,0.0002256733,0.0001319968,0.0003019863,0.0002622506,0.0002854779,0.001908157],"category_scores_gemma":[0.0001133741,0.00007302043,0.0003804673,0.0001442802,0.0002318119,0.0002162721,0.0002629972,0.0006893204,0.0003231585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002280235,"about_ca_system_score_gemma":0.0002518145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009692486,"about_ca_topic_score_gemma":0.001059888,"domain_scores_codex":[0.999864,0.00001599887,0.00001697383,0.00001944282,0.00004174138,0.00004189848],"domain_scores_gemma":[0.9999312,0.00001107439,0.00002265704,0.000007700191,0.000009555354,0.00001777398],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002844567,0.00005601045,0.0001708604,0.0001068486,0.000006770549,0.0001057058,0.00001206754,0.0001043506,0.9949954,0.0004606204,0.0003008574,0.00339604],"study_design_scores_gemma":[0.00001109179,0.0002303177,0.001959855,0.00001045295,0.000005762592,0.0002127737,0.00001446745,0.0002378534,0.9940801,0.00006293534,0.003169128,0.000005134661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9497679,0.01999252,0.007483905,0.001732043,0.0004603981,0.0001258875,0.002235368,0.0003904433,0.01781156],"genre_scores_gemma":[0.9879003,0.004191685,0.00318142,0.0003420826,0.00003335252,0.00002794428,0.0006669617,0.00002191421,0.003634361],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001908157,"threshold_uncertainty_score":0.006383419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007727288663011106,"score_gpt":0.2159199554957584,"score_spread":0.2081926668327473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}