{"id":"W4309243908","doi":"10.1128/spectrum.03183-22","title":"<i>Candida albicans</i> Reactive Oxygen Species (ROS)-Dependent Lethality and ROS-Independent Hyphal and Biofilm Inhibition by Eugenol and Citral","year":2022,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":58,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Regina","funders":"Canada Foundation for Innovation; Natural Sciences and Engineering Research Council of Canada; Government of Canada","keywords":"Reactive oxygen species; Biofilm; Candida albicans; Microbiology; Eugenol; Chemistry; Lethality; Biology; Biochemistry; Toxicology; Bacteria; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004682054,0.0002764539,0.0004943867,0.00009155876,0.0004437765,0.00003232015,0.0000692455,0.0001637133,0.0004443051],"category_scores_gemma":[0.00003054439,0.0002565103,0.00006911697,0.0001099885,0.0006373865,0.00008176508,0.0002743816,0.0005821435,0.000004577725],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002369318,"about_ca_system_score_gemma":0.00008491081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004536176,"about_ca_topic_score_gemma":0.0005850532,"domain_scores_codex":[0.9980622,0.0002011837,0.0003230094,0.0007910625,0.0001384585,0.0004840684],"domain_scores_gemma":[0.9993325,0.00007594023,0.0001232846,0.0002657228,0.00003014707,0.000172372],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0007474306,0.0001592842,0.09177022,0.00004550667,0.0000938562,0.00009251935,0.0004012874,1.294744e-7,0.9039199,0.0003203799,0.002222168,0.0002272758],"study_design_scores_gemma":[0.006862353,0.002545179,0.5055175,0.00005359363,0.0003345231,0.003710279,0.005025943,0.00001129591,0.4340837,0.00197654,0.03892445,0.0009545879],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908638,0.002556157,0.00005411493,0.003830283,0.000139703,0.0005336647,0.0009100814,0.00005225553,0.001059916],"genre_scores_gemma":[0.9954524,0.0003746846,0.00006349548,0.001014256,0.00008462172,0.00002716212,0.0003727015,0.00002231557,0.002588343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4698362,"threshold_uncertainty_score":0.9999887,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007727288663011106,"score_gpt":0.2159199554957584,"score_spread":0.2081926668327473,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}